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Mandy G Katz-Jaffe

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Articles 45
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Recent Articles
1.
McCallie B, Haywood M, Henry L, Lee R, Schoolcraft W, Katz-Jaffe M
Biomedicines . 2025 Jan; 13(1). PMID: 39857635
Abnormally fertilized embryos are often discarded during in vitro fertilization due to the fact that known chromosomal ploidy abnormalities lead to implantation failure or pregnancy loss. The objective of this...
2.
Denomme M, McCallie B, Haywood M, Parks J, Schoolcraft W, Katz-Jaffe M
Hum Genomics . 2024 Mar; 18(1):32. PMID: 38532526
Background: Advanced paternal age (APA) is associated with adverse outcomes to offspring health, including increased risk for neurodevelopmental disorders. The aim of this study was to investigate the methylome and...
3.
Yuan Y, Reed L, Swain J, Schoolcraft W, Katz-Jaffe M
Fertil Steril . 2024 Jan; 121(1):121-122. PMID: 38178586
No abstract available.
4.
Russ J, Haywood M, Lane S, Schoolcraft W, Katz-Jaffe M
iScience . 2022 Aug; 25(8):104819. PMID: 35996587
Ovarian aging precedes that of any other mammalian organ and is the primary cause of female age-related infertility. The biological mechanisms responsible for ovarian aging remain unclear. Previous studies have...
5.
Lane S, Reed L, Schoolcraft W, Katz-Jaffe M
Reprod Biomed Online . 2022 Mar; 44(5):858-865. PMID: 35337737
Research Question: What is the reproductive potential of embryos that achieve blastulation on day 7 followed by preimplantation genetic testing for aneuploidies (PGT-A) for infertility patients with slow embryo development?...
6.
Lane S, Parks J, Russ J, Khan S, Schoolcraft W, Yuan Y, et al.
Int J Mol Sci . 2021 Dec; 22(23). PMID: 34884824
Ovarian aging is associated with elevated oxidative stress and diminished oocyte developmental competence. We aimed to determine the impact of systemic antioxidant treatment in aged mice. Female outbred CF-1 mice...
7.
McCallie B, Haywood M, Denomme M, Makloski R, Parks J, Griffin D, et al.
J Assist Reprod Genet . 2021 Mar; 38(7):1853-1860. PMID: 33786734
Purpose: To investigate the biological networks associated with DOR in young women and the subsequent molecular impact on preimplantation embryos. Methods: Whole peripheral blood was collected from patients: young women...
8.
Denomme M, Haywood M, McCallie B, Schoolcraft W, Katz-Jaffe M
Fertil Steril . 2021 Mar; 116(2):309-318. PMID: 33745724
Objective: To evaluate the epigenetic consequence of a prolonged disease state of infertility in euploid blastocysts. Design: Methylome analysis as well as targeted imprinted methylation and expression analysis on individual...
9.
Katz-Jaffe M, Lane S, Parks J, McCallie B, Makloski R, Schoolcraft W
Life (Basel) . 2020 Oct; 10(11). PMID: 33105678
Advanced maternal age (AMA) is associated with reduced fertility due in part to diminished ovarian follicle quantity, inferior oocyte quality, chromosome aneuploidy, and lower implantation rates. Ovarian aging is accompanied...
10.
Pini T, Makloski R, Maruniak K, Schoolcraft W, Katz-Jaffe M
Antioxidants (Basel) . 2020 Jul; 9(7). PMID: 32640607
Sperm DNA damage is correlated with reduced embryo development and increased miscarriage risk, reducing successful conception. Given its links with oxidative stress, antioxidants have been investigated as a potential treatment,...