David K Gardner
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Explore the profile of David K Gardner including associated specialties, affiliations and a list of published articles.
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Articles
142
Citations
2674
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Recent Articles
1.
Georgiou E, Mizrachi Y, Kelley R, Stock-Myer S, Stevens J, Gardner D, et al.
Aust N Z J Obstet Gynaecol
. 2025 Jan;
PMID: 39865443
Background: Modern assisted reproductive technology (ART), including pre-implantation genetic testing for aneuploidy (PGT-A), has opened new avenues in understanding early embryonic events and has simultaneously raised questions about the impact...
2.
Gurner K, Gardner D
Biomolecules
. 2025 Jan;
15(1).
PMID: 39858494
The blastocyst develops a unique metabolism that facilitates the creation of a specialized microenvironment at the site of implantation characterized by high levels of lactate and reduced pH. While historically...
3.
Vasilescu S, Goss D, Gurner K, Kelley R, Mazi M, De Bond F, et al.
Reprod Biomed Online
. 2024 Dec;
50(2):104433.
PMID: 39721152
Research Question: Can a biomimetic microfluidic sperm sorter isolate motile sperm while minimizing DNA damage in comparison with density gradient centrifugation (DGC)? Design: This was a two-phase study of 61...
4.
Harvey A, Willson B, Surrey E, Gardner D
Fertil Steril
. 2024 Aug;
123(1):10-21.
PMID: 39197516
Ovarian stimulation (OS) truly is an art. There exists a myriad of protocols used to achieve the same goal: stimulating the ovaries to produce more than one mature oocyte to...
5.
Illingworth P, Venetis C, Gardner D, Nelson S, Berntsen J, Larman M, et al.
Nat Med
. 2024 Aug;
30(11):3114-3120.
PMID: 39122964
To assess the value of deep learning in selecting the optimal embryo for in vitro fertilization, a multicenter, randomized, double-blind, noninferiority parallel-group trial was conducted across 14 in vitro fertilization...
6.
Tremellen K, Alfer J, Cotan D, Perez-Sanchez M, Harvey A, Gardner D
Reprod Biomed Online
. 2024 Jul;
49(4):104107.
PMID: 39067212
Research Question: Does the application of a micro-dose of copper chloride gel increase endometrial production of vascular endothelial growth factor (VEGF) without compromising endometrial function or producing embryo toxicity? Design:...
7.
Oberin R, Petautschnig S, Jarred E, Qu Z, Tsai T, Youngson N, et al.
Elife
. 2024 May;
13.
PMID: 38813868
Germline epigenetic programming, including genomic imprinting, substantially influences offspring development. Polycomb Repressive Complex 2 (PRC2) plays an important role in Histone 3 Lysine 27 trimethylation (H3K27me3)-dependent imprinting, loss of which...
8.
Gurner K, Kelley R, Lee L, Gardner D
Reprod Biomed Online
. 2024 Apr;
48(6):103847.
PMID: 38657328
Research Question: What impact do variations in embryo transfer catheter loading and movement procedures have on temperature and pH fluctuations during embryo transfer? Design: Mock embryo transfers were conducted to...
9.
Goss D, Vasilescu S, Vasilescu P, Cooke S, Kim S, Sacks G, et al.
Reprod Biomed Online
. 2024 Apr;
49(1):103910.
PMID: 38652944
Research Question: Can artificial intelligence (AI) improve the efficiency and efficacy of sperm searches in azoospermic samples? Design: This two-phase proof-of-concept study began with a training phase using eight azoospermic...
10.
Whatley E, Harvey A, Gardner D
Reproduction
. 2024 Apr;
167(6).
PMID: 38593828
In Brief: A ketogenic diet (KD) elevates blood β-hydroxybutyrate to concentrations that are known to perturb the development, metabolism, histone acetylation and viability of preimplantation mouse embryos in culture. This...