Mande Holford
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Explore the profile of Mande Holford including associated specialties, affiliations and a list of published articles.
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40
Citations
404
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Recent Articles
1.
Naidu P, Holford M
Immunology
. 2024 Aug;
173(4):605-621.
PMID: 39188052
The innate immune response is under selection pressures from changing environments and pathogens. While sequence evolution can be studied by comparing rates of amino acid mutations within and between species,...
2.
Fedosov A, Zaharias P, Lemarcis T, Modica M, Holford M, Oliverio M, et al.
Syst Biol
. 2024 Mar;
73(3):521-531.
PMID: 38456663
The molluskan order Neogastropoda encompasses over 15,000 almost exclusively marine species playing important roles in benthic communities and in the economies of coastal countries. Neogastropoda underwent intensive cladogenesis in the...
3.
Achimba F, Faezov B, Cohen B, Dunbrack R, Holford M
Mol Cancer Ther
. 2023 Nov;
23(2):139-147.
PMID: 38015557
The regulation of cellular processes by ion channels has become central to the study of cancer mechanisms. Designing molecules that can modify ion channels specific to tumor cells is a...
4.
Cerullo A, McDermott M, Pepi L, Liu Z, Barry D, Zhang S, et al.
Nat Commun
. 2023 Sep;
14(1):5361.
PMID: 37660066
Every animal secretes mucus, placing them among the most diverse biological materials. Mucus hydrogels are complex mixtures of water, ions, carbohydrates, and proteins. Uncertainty surrounding their composition and how interactions...
5.
Romano J, Li H, Napolitano T, Realubit R, Karan C, Holford M, et al.
Toxins (Basel)
. 2023 Jul;
15(7).
PMID: 37505720
Venoms are a diverse and complex group of natural toxins that have been adapted to treat many types of human disease, but rigorous computational approaches for discovering new therapeutic activities...
6.
Achrak E, Ferd J, Schulman J, Dang T, Krampis K, Holford M
Methods Mol Biol
. 2022 Jun;
2498:89-97.
PMID: 35727542
Animal venoms are among the most complex natural secretions known, comprising a mixture of bioactive compounds often referred to as toxins. Venom arsenals are predominately made up of cysteine-rich peptide...
7.
Holford M, Normark B
Integr Comp Biol
. 2021 Nov;
61(6):1984-1990.
PMID: 34788424
No abstract available.
8.
McDermott M, Cerullo A, Parziale J, Achrak E, Sultana S, Ferd J, et al.
Front Bioeng Biotechnol
. 2021 Oct;
9:734023.
PMID: 34708024
Mucins are a highly glycosylated protein family that are secreted by animals for adhesion, hydration, lubrication, and other functions. Despite their ubiquity, animal mucins are largely uncharacterized. Snails produce mucin...
9.
Grillo C, Holford M, Walter N
Integr Comp Biol
. 2021 Jul;
61(6):2048-2052.
PMID: 34254127
In this future-spanning perspective, we examine how an agent-based model could be used to define general rules for interactions across biological systems and evolutionary time. To date, there have been...
10.
Gorson J, Fassio G, Lau E, Holford M
Toxins (Basel)
. 2021 Feb;
13(2).
PMID: 33540609
Predator-prey interactions are thought to play a driving role in animal evolution, especially for groups that have developed venom as their predatory strategy. However, how the diet of venomous animals...