Man-Wook Hur
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Explore the profile of Man-Wook Hur including associated specialties, affiliations and a list of published articles.
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56
Citations
729
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Recent Articles
1.
Park S, Shin D, Yoon Y, Park S, Im S, Kim Y, et al.
Biochim Biophys Acta Gene Regul Mech
. 2024 Apr;
1867(2):195030.
PMID: 38670485
Antiretroviral therapy-naive people living with HIV possess less fat than people without HIV. Previously, we found that HIV-1 transactivator of transcription (TAT) decreases fat in ob/ob mice. The TAT38 (a.a....
2.
Choi S, Cho S, Park S, Hur M
Biochim Biophys Acta Gene Regul Mech
. 2023 Apr;
1866(2):194931.
PMID: 37011832
ZBTB7A overexpressed in many human cancers is a major oncogenic driver. ZBTB7A promotes tumorigenesis by regulating transcription of the genes involved in cell survival and proliferation, apoptosis, invasion, and migration/metastasis....
3.
Choi W, Yoon J, Choi S, Jeon B, Kim H, Hur M
Exp Mol Med
. 2021 May;
53(5):917-932.
PMID: 34017061
Zbtb7c is a proto-oncoprotein that controls the cell cycle and glucose, glutamate, and lipid metabolism. Zbtb7c expression is increased in the liver and white adipose tissues of aging or high-fat...
4.
Choi S, Koh D, Ahn H, Kim J, Kim Y, Hur M
Biochem Biophys Res Commun
. 2020 Oct;
533(4):1247-1254.
PMID: 33051058
The oncoprotein, c-Myc, not only promotes cell proliferation, but can also induce or sensitize cells to apoptosis. However, how c-Myc decides cell fate and which c-Myc downstream target genes are...
5.
Choi S, Cho S, Song J, Hur M
Biochem Biophys Res Commun
. 2020 Aug;
530(3):588-596.
PMID: 32753315
KLHL4 is a member of the KLHL protein family, many of whom bind the Cul3 E3 ligase, and mediate the ubiquitination of interacting proteins. The KLHL4 gene, localized on the...
6.
Choi S, Koh D, Cho S, Kim M, Kim K, Hur M
J Biol Chem
. 2019 Jul;
294(35):12957-12974.
PMID: 31296660
Transcriptional regulator KAISO plays a critical role in cell cycle arrest and apoptosis through modulation of p53 acetylation by histone acetyltransferase p300. KAISO potently stimulates apoptosis in cells expressing WT...
7.
Choi S, Kim M, Yoon Y, Koh D, Kim M, Cho S, et al.
Biochim Biophys Acta Gene Regul Mech
. 2019 Jul;
1862(8):771-785.
PMID: 31271899
Overexpressed Solute Carrier Family 16 Member 3 (SLC16A3, also called MCT4) plays a critical role in hypoxic cancer cell growth and proliferation, by expelling glycolysis-derived lactate across the plasma membrane....
8.
Jeon B, Song J, Huh J, Yang W, Hur M
FEBS Lett
. 2019 Jun;
593(18):2665-2674.
PMID: 31222731
Dysregulated matrix metalloproteinase (MMP) gene expression is a major cause of the degradation of lung tissue that is integral to emphysema pathogenesis. Cigarette smoking (CS) increases MMP gene expression, a...
9.
Song J, Lee S, Kim M, Jeon B, Cho S, Lee S, et al.
FEBS Lett
. 2019 May;
593(14):1763-1776.
PMID: 31127867
The protein deacetylase SIRT1 is crucial to numerous physiological processes, such as aging, metabolism, and autoimmunity, and is repressed by various transcription factors, including HIC1. Conversely, we found that HIC2,...
10.
Choi W, Yoon J, Song J, Jeon B, Park J, Koh D, et al.
Biochim Biophys Acta Gene Regul Mech
. 2019 Apr;
1862(6):643-656.
PMID: 30959128
Gluconeogenesis is essential for blood glucose homeostasis during fasting and is regulated by various enzymes, which are encoded by gluconeogenic genes. Those genes are controlled by various transcription factors. Zinc...