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Man-Lung Fung

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Articles 64
Citations 1042
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Recent Articles
1.
Zhang J, Tsui K, Lee H, Aquili L, Wong K, Kocabicak E, et al.
Int J Mol Sci . 2025 Jan; 26(1. PMID: 39796199
Melatonin is a hormone released by the pineal gland that regulates the sleep-wake cycle. It has been widely studied for its therapeutic effects on Alzheimer's disease (AD), particularly through the...
2.
Chau S, Chong P, Jin H, Tsui K, Khairuddin S, Tse A, et al.
Int J Mol Sci . 2023 Apr; 24(7). PMID: 37047062
Cerebellar ataxia is a neurodegenerative disorder with no definitive treatment. Although previous study demonstrated the neuroprotective effects of (), the mechanisms of . treatment on the neuroinflammatory response, neurotransmission, and...
3.
Poon C, Liu Y, Pak S, Zhao R, Aquili L, Tipoe G, et al.
Aging Dis . 2023 Feb; 14(1):112-135. PMID: 36818556
Declining global DNA methylation and cognitive impairment are reported to occur in the normal aging process. It is not known if DNA methylation plays a role in the efficacy of...
4.
Tsui K, Roy J, Chau S, Wong K, Shi L, Poon C, et al.
Front Aging Neurosci . 2022 Aug; 14:964336. PMID: 35966777
Alzheimer's disease (AD) is the most common form of dementia. Although previous studies have selectively investigated the localization of amyloid-beta (Aβ) deposition in certain brain regions, a comprehensive characterization of...
5.
Flores A, Yu W, Fung M, Lim L
Brain Res Bull . 2022 Jul; 188:92-107. PMID: 35853529
The 'neurogenesis hypothesis of depression' emphasizes the importance of upregulated hippocampal neurogenesis for the efficacy of antidepressant treatment. Neuromodulation is a promising therapeutic method that stimulates neural circuitries to treat...
6.
Yu W, Tse A, Guan L, Chiu J, Tan S, Khairuddin S, et al.
Brain Stimul . 2022 May; 15(3):843-856. PMID: 35640844
Background: Given that visual impairment is bi-directionally associated with depression, we examined whether transcorneal electrical stimulation (TES), a non-invasive treatment for visual disorders, can ameliorate depressive symptoms. Objective: The putative...
7.
Chong P, Poon C, Roy J, Tsui K, Lew S, Phang M, et al.
Chin Med . 2021 Dec; 16(1):132. PMID: 34876186
Background: Depression is a severe neuropsychiatric disorder that affects more than 264 million people worldwide. The efficacy of conventional antidepressants are barely adequate and many have side effects. Hericium erinaceus...
8.
Chan H, Yanshree , Roy J, Tipoe G, Fung M, Lim L
Int J Mol Sci . 2021 Sep; 22(18). PMID: 34576314
Alzheimer's disease (AD) is a progressive debilitating neurodegenerative disease and the most common form of dementia in the older population. At present, there is no definitive effective treatment for AD....
9.
Roy J, Tsui K, Ng J, Fung M, Lim L
Int J Mol Sci . 2021 Jul; 22(13). PMID: 34202125
Alzheimer's disease is a neurodegenerative disorder associated with age, and is characterized by pathological markers such as amyloid-beta plaques and neurofibrillary tangles. Symptoms of AD include cognitive impairments, anxiety and...
10.
Khairuddin S, Ngo F, Lim W, Aquili L, Khan N, Fung M, et al.
J Clin Med . 2020 Oct; 9(10). PMID: 33053848
Major depression contributes significantly to the global disability burden. Since the first clinical study of deep brain stimulation (DBS), over 406 patients with depression have now undergone this neuromodulation therapy,...