Mamoru Ohkita
Overview
Explore the profile of Mamoru Ohkita including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
74
Citations
603
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Tawa M, Nakagawa K, Ohkita M
Hypertens Res
. 2025 Jan;
PMID: 39833553
Poor blood pressure control in treated patients with hypertension is an important topic in the field of hypertension, and an unmet need for new therapeutic drugs remains. Soluble guanylate cyclase...
2.
Tawa M, Nakagawa K, Ohkita M
J Pharmacol Sci
. 2024 Dec;
157(1):1-7.
PMID: 39706640
Nitric oxide (NO)-donor drugs, which stimulate reduced form of soluble guanylate cyclase (sGC), have different efficacy to the arteries and veins. This study examined whether sGC activators, which activate oxidized/apo...
3.
Tawa M, Nakagawa K, Ohkita M
J Pharmacol Exp Ther
. 2024 Jan;
390(3):280-287.
PMID: 38262743
Ischemia with non-obstructive coronary arteries (INOCA), caused by coronary artery spasm, has gained increasing attention owing to the poor quality of life of impacted patients. Therapeutic options to address INOCA...
4.
Effects of beetroot juice supplementation on vascular functional and structural changes in aged mice
Tawa M, Nakagawa K, Ohkita M
Physiol Rep
. 2023 Jun;
11(12):e15755.
PMID: 37340325
This study investigated whether beetroot juice (BRJ) ingestion ameliorates aging-induced functional and structural changes in vasculature. Aged mice (98-100 weeks old) were supplemented with BRJ (nitrate: 3.5 mmol/L) or drinking...
5.
Nakagawa K, Kobayashi F, Kamei Y, Tawa M, Ohkita M
Biol Pharm Bull
. 2022 Apr;
45(4):522-527.
PMID: 35370278
The accumulation of uremic toxins is known to be one of the causes of cardiovascular disorder related to renal disease. Among the many uremic toxins, we focused on kynurenine (kyn),...
6.
Nakagawa K, Tanaka R, Donouchi M, Kanda M, Kamada S, Kobuchi S, et al.
Oxid Med Cell Longev
. 2022 Mar;
2022:7547269.
PMID: 35251481
Chronic kidney disease (CKD) and cardiovascular disease are known to be linked, and the involvement of indoxyl sulfate (IS), a type of uremic toxin, has been suggested as one of...
7.
Tawa M, Shimosato T, Nakagawa K, Okamura T, Ohkita M
Pharmacology
. 2021 Dec;
107(3-4):235-240.
PMID: 34929695
Soluble guanylate cyclase (sGC) plays an important role in nitric oxide (NO)-mediated regulation of vascular tone; however, NO bioavailability is often reduced in diseased blood vessels. Accumulating evidence suggests that...
8.
Tawa M, Nagata R, Sumi Y, Nakagawa K, Sawano T, Ohkita M, et al.
PLoS One
. 2021 Apr;
16(4):e0249816.
PMID: 33831045
Beetroot (Beta vulgaris L.) has a high level of nitrate; therefore, its dietary intake could increase nitric oxide (NO) level in the body, possibly preventing the development of pulmonary hypertension...
9.
Nakagawa K, Itoya M, Takemoto N, Matsuura Y, Tawa M, Matsumura Y, et al.
Life Sci
. 2020 Nov;
265:118807.
PMID: 33232689
Aims: The uremic toxin indoxyl sulfate (IS) was reported to be the cause of cardiovascular disease associated with chronic kidney disease. Therefore, we evaluated the direct influences of IS on...
10.
Sato A, Nishioka S, Kiuchi M, Imada Y, Makino K, Nakagawa K, et al.
Biol Pharm Bull
. 2020 Jan;
43(1):59-67.
PMID: 31902933
Grape extract (GE), which contains various polyphenolic compounds, exerts protective effects against lifestyle-related diseases, such as diabetes and hypertension. We pharmacologically investigated whether dietary supplements with an extract from Chardonnay...