Malini Raghavan
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Explore the profile of Malini Raghavan including associated specialties, affiliations and a list of published articles.
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60
Citations
957
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Recent Articles
11.
Maiers M, Mehr R, Raghavan M, Kaufman J, Louzoun Y
Front Immunol
. 2021 Jun;
12:701398.
PMID: 34079561
No abstract available.
12.
Venkatesan A, Satin L, Raghavan M
Prog Mol Subcell Biol
. 2021 May;
59:145-162.
PMID: 34050865
The endoplasmic reticulum (ER) is an organelle that mediates the proper folding and assembly of proteins destined for the cell surface, the extracellular space and subcellular compartments such as the...
13.
Venkatesan A, Geng J, Kandarpa M, Wijeyesakere S, Bhide A, Talpaz M, et al.
J Cell Biol
. 2021 Apr;
220(7).
PMID: 33909030
Myeloproliferative neoplasms (MPNs) are frequently driven by mutations within the C-terminal domain (C-domain) of calreticulin (CRT). CRTDel52 and CRTIns5 are recurrent mutations. Oncogenic transformation requires both mutated CRT and the...
14.
Geng J, Raghavan M
Curr Opin Immunol
. 2021 Apr;
70:67-74.
PMID: 33857912
Major histocompatibility complex class I (MHC-I) molecules play a critical role in both innate and adaptive immune responses. The heterodimeric complex of a polymorphic MHC-I heavy chain and a conserved...
15.
Kavadichanda C, Geng J, Bulusu S, Negi V, Raghavan M
Front Immunol
. 2021 Mar;
12:601518.
PMID: 33763060
Heritability of Spondyloarthritis (SpA) is highlighted by several familial studies and a high association with the presence of human leukocyte antigen (HLA)-B27. Though it has been over four decades since...
16.
Assessments of HLA-I Specificities of Anti-HLA-I Monoclonal Antibodies Using Solid Phase Bead Arrays
Zaitouna A, Ramon D, Raghavan M
Bio Protoc
. 2021 Mar;
10(12):e3655.
PMID: 33659325
Human leukocyte antigen class I (HLA-I) molecules are a group of structurally-related cell surface proteins with a high degree of variability within the population. While only up to six variants...
17.
Bashirova A, Viard M, Naranbhai V, Grifoni A, Garcia-Beltran W, Akdag M, et al.
Proc Natl Acad Sci U S A
. 2020 Oct;
117(45):28232-28238.
PMID: 33097667
Human leukocyte antigen (HLA) class I allotypes vary in their ability to present peptides in the absence of tapasin, an essential component of the peptide loading complex. We quantified tapasin...
18.
Zaitoua A, Kaur A, Raghavan M
F1000Res
. 2020 Oct;
9.
PMID: 33014341
Major histocompatibility class I (MHC-I) proteins mediate immunosurveillance against pathogens and cancers by presenting antigenic or mutated peptides to antigen receptors of CD8+ T cells and by engaging receptors of...
19.
Mohan H, Yang B, Dean N, Raghavan M
J Biol Chem
. 2020 Sep;
295(49):16754-16772.
PMID: 32978262
α1-antitrypsin (AAT) regulates the activity of multiple proteases in the lungs and liver. A mutant of AAT (E342K) called ATZ forms polymers that are present at only low levels in...
20.
Painter M, Zimmerman G, Merlino M, Robertson A, Terry V, Ren X, et al.
Proc Natl Acad Sci U S A
. 2020 Sep;
117(38):23835-23846.
PMID: 32900948
Nef is an HIV-encoded accessory protein that enhances pathogenicity by down-regulating major histocompatibility class I (MHC-I) expression to evade killing by cytotoxic T lymphocytes (CTLs). A potent Nef inhibitor that...