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Malgorzata Burek

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Articles 49
Citations 1327
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Recent Articles
1.
Curtaz C, Harms J, Schmitt C, Sauer S, Christner S, Kessler A, et al.
Cancers (Basel) . 2025 Jan; 17(2). PMID: 39858042
Breast cancer patients who develop brain metastases have a high mortality rate and a massive decrease in quality of life. Approximately 10-15% of all patients with breast cancer (BC) and...
2.
Teles R, Villarinho N, Yamagata A, Hiroki C, de Oliveira M, Tercarioli G, et al.
BBA Adv . 2025 Jan; 7():100130. PMID: 39802400
Metastases are the leading cause of cancer-related deaths, and their origin is not fully elucidated. Recently, studies have shown that extracellular vesicles (EVs), particularly small extracellular vesicles (sEV), can disrupt...
3.
Teles R, Engelmayr D, Meybohm P, Burek M
Methods Mol Biol . 2024 Mar; 2761:39-48. PMID: 38427227
Extracellular vesicles (EVs) are small lipid bilayer vesicles released by cells to facilitate cell-to-cell communication. To study their biological roles and functions, they need to be isolated and purified, which...
4.
Mi J, Sun A, Hartel L, Dilling C, Meybohm P, Burek M
Methods Mol Biol . 2024 Mar; 2761:27-38. PMID: 38427226
The integrity of the blood-brain barrier (BBB) is essential for the normal functioning of the central nervous system (CNS). Isolated brain capillaries are essential for analyzing changes in protein and...
5.
Reinhold A, Hartmannsberger B, Burek M, Rittner H
Pharmacol Ther . 2023 Jun; 249:108484. PMID: 37390969
Chronic and neuropathic pain are a widespread burden. Incomplete understanding of underlying pathomechanisms is one crucial factor for insufficient treatment. Recently, impairment of the blood nerve barrier (BNB) has emerged...
6.
Li L, Kreye J, Burek M, Cordero-Gomez C, Barthel P, Sanchez-Sendin E, et al.
Front Cell Neurosci . 2023 Feb; 17:1077204. PMID: 36794262
The antibody repertoire from CSF-derived antibody-secreting cells and memory B-cells in patients with encephalitis contains a considerable number of antibodies that do not target the disease-defining autoantigen such as the...
7.
Salvador E, Koppl T, Hormann J, Schonharl S, Bugaeva P, Kessler A, et al.
Pharmaceutics . 2023 Jan; 15(1). PMID: 36678814
In a recent study, we showed in an in vitro murine cerebellar microvascular endothelial cell (cerebEND) model as well as in vivo in rats that Tumor-Treating Fields (TTFields) reversibly open...
8.
Nowacka-Chmielewska M, Grabowska K, Grabowski M, Meybohm P, Burek M, Malecki A
Int J Mol Sci . 2022 Nov; 23(21). PMID: 36362131
Chronic stress, even stress of a moderate intensity related to daily life, is widely acknowledged to be a predisposing or precipitating factor in neuropsychiatric diseases. There is a clear relationship...
9.
Curtaz C, Kiesel L, Meybohm P, Wockel A, Burek M
Cancers (Basel) . 2022 Oct; 14(20). PMID: 36291916
The molecular receptor status of breast cancer has implications for prognosis and long-term metastasis. Although metastatic luminal B-like, hormone-receptor-positive, HER2-negative, breast cancer causes brain metastases less frequently than other subtypes,...
10.
Salvador E, Kessler A, Domrose D, Hormann J, Schaeffer C, Giniunaite A, et al.
Biomolecules . 2022 Oct; 12(10). PMID: 36291557
Despite the availability of numerous therapeutic substances that could potentially target CNS disorders, an inability of these agents to cross the restrictive blood-brain barrier (BBB) limits their clinical utility. Novel...