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Mal-Gi Choi

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Articles 12
Citations 402
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Recent Articles
1.
Nguyen T, Hoang T, Nguyen T, Jeong C, Tran T, Choi M, et al.
PLoS One . 2024 Aug; 19(8):e0308370. PMID: 39121049
Human hyaluronidase 1 (HYAL1) and PH20 play vital roles in degrading hyaluronic acids through the substrate-assisted double displacement mechanism. While HYAL1, a lysosomal enzyme, functions optimally under acidic conditions, PH20,...
2.
Choi M, Kim M, Kim D, Yu R, Jang Y, Oh W
PLoS One . 2018 Apr; 13(4):e0195339. PMID: 29608598
α-Synuclein (α-syn) is a major component of Lewy bodies found in synucleinopathies including Parkinson's disease (PD) and Dementia with Lewy Bodies (DLB). Under the pathological conditions, α-syn tends to generate...
3.
Bae W, Choi M, Hyeon C, Shin Y, Yoon T
J Am Chem Soc . 2013 Oct; 135(43):16242. PMID: 24131366
No abstract available.
4.
Bae W, Bae W, Choi M, Hyeon C, Shin Y, Yoon T
J Am Chem Soc . 2013 Jul; 135(28):10254-7. PMID: 23808880
Current single-molecule techniques do not permit the real-time observation of multiple proteins interacting closely with each other. We here report an approach enabling us to determine the single-molecule fluorescence resonance...
5.
Choi B, Choi M, Kim J, Yang Y, Lai Y, Kweon D, et al.
Proc Natl Acad Sci U S A . 2013 Feb; 110(10):4087-92. PMID: 23431141
Parkinson disease and dementia with Lewy bodies are featured with the formation of Lewy bodies composed mostly of α-synuclein (α-Syn) in the brain. Although evidence indicates that the large oligomeric...
6.
Kim J, Choi B, Choi M, Kim S, Lai Y, Shin Y, et al.
EMBO J . 2012 Mar; 31(9):2144-55. PMID: 22407297
Synaptotagmin-1 (Syt1) is a major Ca(2+) sensor for synchronous neurotransmitter release, which requires vesicle fusion mediated by SNAREs (soluble N-ethylmaleimide-sensitive factor attachment protein receptors). Syt1 utilizes its diverse interactions with...
7.
Choi M, Lee E, Chung H, Jang S, Lee C
BMB Rep . 2011 Jul; 44(7):458-61. PMID: 21777516
Enteropeptidase is a serine protease secreted by the pancreas and converts inactive trypsinogen to active trypsin. Enteropeptidase cleaves the C-terminal end of the substrate recognition sequence Asp-Asp-Asp-Asp-Lys (D(4)K). The assay...
8.
Schulz T, Choi M, Raychaudhuri S, Mears J, Ghirlando R, Hinshaw J, et al.
J Cell Biol . 2009 Dec; 187(6):889-903. PMID: 20008566
Sterols are transferred between cellular membranes by vesicular and poorly understood nonvesicular pathways. Oxysterol-binding protein-related proteins (ORPs) have been implicated in sterol sensing and nonvesicular transport. In this study, we...
9.
Choi M, Carman G
J Biol Chem . 2006 Dec; 282(8):5367-77. PMID: 17189248
CTP synthetase is an essential enzyme that generates the CTP required for the synthesis of nucleic acids and membrane phospholipids. In this study, we examined the phosphorylation of the human...
10.
Han G, Sreenivas A, Choi M, Chang Y, Martin S, Baldwin E, et al.
J Biol Chem . 2005 Sep; 280(46):38328-36. PMID: 16179339
CTP synthetase (EC 6.3.4.2, UTP:ammonia ligase (ADP-forming)) is an essential enzyme in all organisms; it generates the CTP required for the synthesis of nucleic acids and membrane phospholipids. In this...