Majid Mehravar
Overview
Explore the profile of Majid Mehravar including associated specialties, affiliations and a list of published articles.
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12
Citations
62
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Recent Articles
1.
Mehravar M, Wong J
Curr Opin Genet Dev
. 2024 Jun;
87:102211.
PMID: 38838495
N-methyladenosine (mA) is the most abundant modification to mRNAs. Loss-of-function studies of main mA regulators have indicated the role of mA in pre-mRNA splicing. Recent studies have reported the role...
2.
Pinello N, Song R, Lee Q, Calonne E, Duan K, Wong E, et al.
Cell Mol Life Sci
. 2024 May;
81(1):229.
PMID: 38780787
RNA modifications are essential for the establishment of cellular identity. Although increasing evidence indicates that RNA modifications regulate the innate immune response, their role in monocyte-to-macrophage differentiation and polarisation is...
3.
Mehravar M, Ghaemimanesh F, Poursani E
Cancer Biomark
. 2022 Mar;
34(4):563-570.
PMID: 35275520
Background: Secreted phosphoprotein 1 (SPP1), also known as osteopontin (OPN), is a multifunctional protein expressed in diverse normal tissues, and functionally is involved in cellular matrix and signaling processes. Many...
4.
Mehravar M, Ghaemimanesh F, Poursani E
BMC Genomics
. 2021 Oct;
22(1):718.
PMID: 34610795
Background: Overlapping genes share same genomic regions in parallel (sense) or anti-parallel (anti-sense) orientations. These gene pairs seem to occur in all domains of life and are best known from...
5.
Ghaemimanesh F, Mehravar M, Milani S, Poursani E, Saliminejad K
J Cell Physiol
. 2021 Feb;
236(9):6271-6281.
PMID: 33634506
Sortilin (also known as neurotensin receptor 3) is a multitasking protein implicated in numerous pathophysiological processes, including cancer development, cardiovascular impairment, Alzheimer-type dementia, and depression. Although the definitive role of...
6.
Mehravar M, Ghaemimanesh F, Poursani E
Stem Cell Rev Rep
. 2021 Jan;
17(4):1121-1136.
PMID: 33389631
OCT4 plays critical roles in self-renewal and pluripotency maintenance of embryonic stem cells, and is considered as one of the main stemness markers. It also has pivotal roles in early...
7.
Mehravar M, Poursani E
Stem Cell Rev Rep
. 2020 Nov;
17(3):1068-1073.
PMID: 33241484
Alternative promoter and alternative splicing are two important mechanisms of gene regulation and protein diversity in different physiological contexts of eukaryotes, especially in stem cells and developmental stages. Pou5f1 gene...
8.
Poursani E, Mehravar M, Shahryari A, Mowla S, Mohammad Soltani B
Avicenna J Med Biotechnol
. 2017 Nov;
9(4):201-204.
PMID: 29090070
Background: The human gene, responsible for pluripotency and self-renewal of Embryonic Stem (ES) and Embryonic Carcinoma (EC) cells, can generate several transcripts (OCT4A, OCT4B-variant 2, OCT4B-variant 3, OCT4B-variant 5, OCT4B1,...
9.
Poursani E, Mehravar M, Mohammad Soltani B, Mowla S
Tumour Biol
. 2017 Oct;
39(10):1010428317724280.
PMID: 29022482
OCT4 is a crucial transcription factor that maintains self-renewal and pluripotency of embryonic stem and embryonic carcinoma cells. The human OCT4 gene can generate at least three variants (OCT4A, OCT4B,...
10.
Poursani E, Mehravar M, Mohammad Soltani B, Mowla S, Trosko J
Avicenna J Med Biotechnol
. 2017 Jul;
9(3):142-145.
PMID: 28706610
Background: Alternative splicing is an important mechanism that regulates gene expression and function in human cells. , a crucial pluripotency marker in embryonic stem/carcinoma cells generates several spliced variants in...