Francois Fuks
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Explore the profile of Francois Fuks including associated specialties, affiliations and a list of published articles.
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89
Citations
6568
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Recent Articles
1.
Quarto G, Li Greci A, Bizet M, Penning A, Primac I, Murisier F, et al.
Cell
. 2025 Jan;
188(4):998-1018.e26.
PMID: 39826545
The marking of DNA, histones, and RNA is central to gene expression regulation in development and disease. Recent evidence links N6-methyladenosine (mA), installed on RNA by the METTL3-METTL14 methyltransferase complex,...
2.
Bonfim M, Aitchedji C, Van Goethem F, Sauvage L, Poinsot T, Calonne E, et al.
Front Microbiol
. 2025 Jan;
15:1501061.
PMID: 39744389
Type 1 diabetes (T1D) is characterized by a prolonged autoimmune attack resulting in the massive loss of insulin-producing beta cells. The initiation and progression of T1D depends on a complex...
3.
4.
Yao Y, Lv H, Zhang M, Li Y, Herman J, Brock M, et al.
Front Med
. 2024 Jun;
18(4):721-734.
PMID: 38926248
Synthetic lethality is a novel model for cancer therapy. To understand the function and mechanism of BEN domain-containing protein 4 (BEND4) in pancreatic cancer, eight cell lines and a total...
5.
Pinello N, Song R, Lee Q, Calonne E, Duan K, Wong E, et al.
Cell Mol Life Sci
. 2024 May;
81(1):229.
PMID: 38780787
RNA modifications are essential for the establishment of cellular identity. Although increasing evidence indicates that RNA modifications regulate the innate immune response, their role in monocyte-to-macrophage differentiation and polarisation is...
6.
Pinello N, Song R, Lee Q, Calonne E, Larance M, Fuks F, et al.
Sci Data
. 2024 Feb;
11(1):252.
PMID: 38418823
RNA modifications have emerged as central regulators of gene expression programs. Amongst RNA modifications are N6-methyladenosine (mA) and RNA 5-hydroxymethylcytosine (5hmC). While mA is established as a versatile regulator of...
7.
Singh B, Tran H, Kramer J, Kirichenko E, Changela N, Wang F, et al.
PLoS One
. 2024 Feb;
19(2):e0293894.
PMID: 38381741
Modifications of mRNA, especially methylation of adenosine, have recently drawn much attention. The much rarer modification, 5-hydroxymethylation of cytosine (5hmC), is not well understood and is the subject of this...
8.
Ma H, Bizet M, Soares Da Costa C, Murisier F, de Bony E, Wang M, et al.
Mol Cell
. 2023 Dec;
83(23):4239-4254.e10.
PMID: 38065062
A common mRNA modification is 5-methylcytosine (mC), whose role in gene-transcript processing and cancer remains unclear. Here, we identify serine/arginine-rich splicing factor 2 (SRSF2) as a reader of mC and...
9.
Chung F, Gonzalez Maldonado S, Nemc A, Bouaoun L, Cahais V, Cuenin C, et al.
Clin Epigenetics
. 2023 Jun;
15(1):102.
PMID: 37309009
Background: Epigenetic alterations are a near-universal feature of human malignancy and have been detected in malignant cells as well as in easily accessible specimens such as blood and urine. These...
10.
Dube G, Tiamiou A, Bizet M, Boumahd Y, Gasmi I, Crake R, et al.
J Exp Clin Cancer Res
. 2023 Mar;
42(1):78.
PMID: 36998085
Background: Aerobic glycolysis, also known as the Warburg effect, is predominantly upregulated in a variety of solid tumors, including breast cancer. We have previously reported that methylglyoxal (MG), a very...