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Maikun Teng

Explore the profile of Maikun Teng including associated specialties, affiliations and a list of published articles. Areas
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Articles 157
Citations 1799
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Recent Articles
1.
Ge Q, Teng M, Li X, Guo Q, Tao Y
Structure . 2022 Dec; 31(1):33-43.e5. PMID: 36513066
The lack of incorporating epitope information into the selection process makes the conventional antibody screening method less effective in identifying antibodies with desired functions. Here, we developed an epitope-directed antibody...
2.
Wang L, Zhang H, Lv P, Li Y, Teng M, Liu Y, et al.
Life (Basel) . 2022 Sep; 12(9). PMID: 36143481
Intracellular fatty acid-binding proteins are evolutionarily highly conserved proteins. The major functions and responsibilities of this family are the regulation of FA uptake and intracellular transport. The structure of the...
3.
Tian T, Chen L, Dou Z, Yang Z, Gao X, Yuan X, et al.
Cell Discov . 2022 Sep; 8(1):90. PMID: 36085283
In mitosis, accurate chromosome segregation depends on kinetochores that connect centromeric chromatin to spindle microtubules. The centromeres of budding yeast, which are relatively simple, are connected to individual microtubules via...
4.
Yang L, He W, Yun Y, Gao Y, Zhu Z, Teng M, et al.
Genomics Proteomics Bioinformatics . 2022 Mar; 20(4):765-779. PMID: 35288344
Uncovering conserved 3D protein-ligand binding patterns on the basis of functional groups (FGs) shared by a variety of small molecules can greatly expand our knowledge of protein-ligand interactions. Despite that...
5.
Wang Q, Lu Q, Guo Q, Teng M, Gong Q, Li X, et al.
Nat Commun . 2022 Jan; 13(1):454. PMID: 35075127
Melatonin receptors (MT and MT in humans) are family A G protein-coupled receptors that respond to the neurohormone melatonin to regulate circadian rhythm and sleep. Numerous efforts have been made...
6.
Li B, Dai X, Xu X, Adili R, Dias Neves M, Lei X, et al.
Sci Rep . 2021 Jun; 11(1):11663. PMID: 34083615
The interaction of platelet GPIbα with von Willebrand factor (VWF) is essential to initiate platelet adhesion and thrombosis, particularly under high shear stress conditions. However, no drug targeting GPIbα has...
7.
Wang Z, Shen H, He B, Teng M, Guo Q, Li X
FEBS J . 2021 May; 288(20):6019-6034. PMID: 33955674
Staphylococcus aureus is a well-known clinical pathogenic bacterium. In recent years, due to the emergence of multiple drug-resistant strains of S. aureus in clinical practice, S. aureus infections have become...
8.
Jiang X, Zhang L, Teng M, Li X
J Biol Chem . 2021 Jan; 295(51):17865-17876. PMID: 33454020
Investigations of bacterial resistance strategies can aid in the development of new antimicrobial drugs as a countermeasure to the increasing worldwide prevalence of bacterial antibiotic resistance. One such strategy involves...
9.
Wang M, Guo Q, Zhu K, Fang B, Yang Y, Teng M, et al.
Proc Natl Acad Sci U S A . 2020 Nov; 117(48):30433-30440. PMID: 33199635
Two-component systems (TCS), which typically consist of a membrane-embedded histidine kinase and a cytoplasmic response regulator, are the dominant signaling proteins for transduction of environmental stimuli into cellular response pathways...
10.
Wang Q, Bian X, Zeng L, Pan F, Liu L, Liang J, et al.
J Biol Chem . 2020 Jun; 295(30):10293-10306. PMID: 32499370
Endolysosomes are key players in cell physiology, including molecular exchange, immunity, and environmental adaptation. They are the molecular targets of some pore-forming aerolysin-like proteins (ALPs) that are widely distributed in...