Maike E van Hezel
Overview
Explore the profile of Maike E van Hezel including associated specialties, affiliations and a list of published articles.
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Articles
10
Citations
123
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Recent Articles
1.
van Manen L, van Hezel M, Boshuizen M, Straat M, de Man A, Dekimpe C, et al.
Vox Sang
. 2021 Jul;
117(1):64-70.
PMID: 34196412
Background And Objectives: Red blood cell (RBC) transfusion is a frequently applied intervention in an intensive care unit. However, transfusion is associated with adverse outcomes including organ failure and thrombo-embolic...
2.
van Manen L, Deurvorst J, van Hezel M, Boshuizen M, van Bruggen R, Juffermans N
Crit Care
. 2020 Aug;
24(1):498.
PMID: 32787902
No abstract available.
3.
van Hezel M, Boshuizen M, Peters A, Straat M, Vlaar A, Spoelstra-de Man A, et al.
Transfusion
. 2019 Dec;
60(2):294-302.
PMID: 31804732
Background: Red blood cell (RBC) transfusion is associated with adverse effects, which may involve activation of the host immune response. The effect of RBC transfusion on neutrophil Reactive Oxygen Species...
4.
van Hezel M, van Manen L, Boshuizen M, Straat M, De Cuyper I, Beuger B, et al.
Thromb Res
. 2019 Nov;
184:115-121.
PMID: 31731068
Introduction: Red blood cell (RBC) transfusion is associated with an increased risk of pro-thrombotic events, but the underlying mechanism is poorly understood. We hypothesized that RBC transfusion modulates platelet activity...
5.
Boshuizen M, van Hezel M, van Manen L, Straat M, Somsen Y, Spoelstra-de Man A, et al.
Transfusion
. 2019 Jan;
59(4):1196-1201.
PMID: 30597563
Background: Anemia of inflammation (AI) has a high prevalence in critically ill patients. In AI, iron metabolism is altered, as high levels of inflammation-induced hepcidin reduce the amount of iron...
6.
van Hezel M, Nieuwland R, van Bruggen R, Juffermans N
Int J Mol Sci
. 2017 Jun;
18(6).
PMID: 28621719
Extracellular vesicles (EVs) can modulate the host immune response, executing both pro- and anti-inflammatory effects. As EVs increasingly gain attention as potential carriers for targeted gene and drug delivery, knowledge...
7.
Peters A, van Hezel M, Klanderman R, Tuip-de Boer A, Wiersinga W, Van Der Spek A, et al.
Transfusion
. 2017 Apr;
57(6):1359-1368.
PMID: 28375559
Background: Transfusion-related immunomodulation (TRIM) encompasses immunosuppressive and proinflammatory effects induced by red blood cell (RBC) transfusion. Changes that occur during storage in the RBC product have been hypothesized to underlie...
8.
Straat M, van Hezel M, Boing A, Tuip-de Boer A, Weber N, Nieuwland R, et al.
Transfusion
. 2016 Dec;
56(12):3012-3020.
PMID: 27933619
Background: Red blood cell (RBC) transfusion is associated with organ failure. The mechanism remains unknown, but may include adherence of blood cells to the microvasculature. We hypothesized that RBC-derived extracellular...
9.
Peters A, van Hezel M, Cortjens B, Tuip-de Boer A, van Bruggen R, de Korte D, et al.
Crit Care Med
. 2016 Mar;
44(6):e412-9.
PMID: 26937863
Objective: Transfusion-related acute lung injury is the leading cause of transfusion-related mortality. Preclinical studies have shown that aged RBCs can induce transfusion-related acute lung injury in the presence of a...
10.
Peters A, van Hezel M, Juffermans N, Vlaar A
Blood Rev
. 2014 Oct;
29(1):51-61.
PMID: 25277811
Transfusion-related acute lung injury (TRALI) is a major cause of transfusion-related mortality. Causative factors are divided in antibody mediated TRALI and non-antibody mediated TRALI. Antibody mediated TRALI is caused by...