Mahmoud G Khalafalla
Overview
Explore the profile of Mahmoud G Khalafalla including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
140
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0
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Recent Articles
1.
Khalafalla M, Tran H, Khalafalla F
Biochim Biophys Acta Rev Cancer
. 2022 Apr;
1877(3):188732.
PMID: 35483490
Despite recent advances in the treatment landscape for prostate cancer, many challenges still remain. A more profound understanding of prostate cancer pathogenesis and the underlying mechanisms is critical to developing...
2.
Pham T, Spaulding C, Shields M, Metropulos A, Shah D, Khalafalla M, et al.
JCI Insight
. 2022 Apr;
7(9).
PMID: 35380995
To elicit effective antitumor responses, CD8+ T cells need to infiltrate tumors and sustain their effector function within the immunosuppressive tumor microenvironment (TME). Here, we evaluate the role of MNK...
3.
Shields M, Spaulding C, Metropulos A, Khalafalla M, Pham T, Munshi H
Cell Rep
. 2022 Mar;
38(9):110441.
PMID: 35235808
Gα13 transduces signals from G-protein-coupled receptors. While Gα13 functions as a tumor suppressor in lymphomas, it is not known whether Gα13 is pro-tumorigenic or tumor suppressive in genetically engineered mouse...
4.
Khalafalla M, Woods L, Jasmer K, Munoz Forti K, Camden J, Jensen J, et al.
Front Pharmacol
. 2020 Apr;
11:222.
PMID: 32231563
Although often overlooked in our daily lives, saliva performs a host of necessary physiological functions, including lubricating and protecting the oral cavity, facilitating taste sensation and digestion and maintaining tooth...
5.
Erb L, Woods L, Khalafalla M, Weisman G
Brain Res Bull
. 2018 Nov;
151:25-37.
PMID: 30472151
Alzheimer's disease (AD) is a progressive neurodegenerative disorder that is characterized by three major histopathological markers: amyloid-β (Aβ) plaques, neurofibrillary tangles and gliosis in the central nervous system (CNS). It...
6.
Khalafalla M, Woods L, Camden J, Khan A, Limesand K, Petris M, et al.
J Biol Chem
. 2017 Aug;
292(40):16626-16637.
PMID: 28798231
Salivary gland inflammation is a hallmark of Sjögren's syndrome (SS), a common autoimmune disease characterized by lymphocytic infiltration of the salivary gland and loss of saliva secretion, predominantly in women....
7.
Woods L, Camden J, El-Sayed F, Khalafalla M, Petris M, Erb L, et al.
PLoS One
. 2015 May;
10(5):e0123641.
PMID: 25955532
Transforming growth factor-β (TGF-β) is a multi-functional cytokine with a well-described role in the regulation of tissue fibrosis and regeneration in the liver, kidney and lung. Submandibular gland (SMG) duct...
8.
El-Sayed F, Camden J, Woods L, Khalafalla M, Petris M, Erb L, et al.
Am J Physiol Cell Physiol
. 2014 Apr;
307(1):C83-96.
PMID: 24760984
Hyposalivation resulting from salivary gland dysfunction leads to poor oral health and greatly reduces the quality of life of patients. Current treatments for hyposalivation are limited. However, regenerative medicine to...