Mahesh A Barmade
Overview
Explore the profile of Mahesh A Barmade including associated specialties, affiliations and a list of published articles.
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8
Citations
92
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Recent Articles
1.
Barmade M, Agrawal P, Rajput S, Murumkar P, Rana B, Sahal D, et al.
RSC Med Chem
. 2024 Feb;
15(2):572-594.
PMID: 38389888
The emergence of drug resistance against the frontline antimalarials is a major challenge in the treatment of malaria. In view of emerging reports on drug-resistant strains of against artemisinin combination...
2.
Chikhale R, Barmade M, Murumkar P, Yadav M
J Med Chem
. 2018 Jun;
61(19):8563-8593.
PMID: 29851474
Decaprenylphosphoryl-β-d-ribose 2'-epimerase (DprE1), a vital enzyme for cell wall synthesis, plays a crucial role in the formation of lipoarabinomannan and arabinogalactan. It was first reported as a druggable target on...
3.
Pal P, Gandhi H, Kanhed A, Patel N, Mankadia N, Baldha S, et al.
Eur J Med Chem
. 2017 Mar;
130:107-123.
PMID: 28242547
A novel series of vicinal diaryl azole-urea derivatives were synthesized and evaluated for their potential to inhibit SOAT enzyme. Among the reported compounds, compound (12d) emerged as the most potent...
4.
Barmade M, Murumkar P, Sharma M, Yadav M
Curr Top Med Chem
. 2016 May;
16(26):2863-2883.
PMID: 27150366
Nitrogen containing heterocyclic rings with an oxygen atom is considered as one of the best combination in medicinal chemistry due to their diversified biological activities. Isoxazole, a five membered heterocyclic...
5.
Yadav M, Barmade M, Tamboli R, Murumkar P
Eur J Med Chem
. 2015 Oct;
105:1-38.
PMID: 26469743
Breast cancer, an emerging disease among the women population, occurs due to overexpression of estrogens. The enzyme aromatase plays a key rate limiting role in the biosynthesis of estrogens. Certain...
6.
Sharma M, Murumkar P, Barmade M, Giridhar R, Yadav M
Expert Opin Ther Pat
. 2015 Jul;
25(10):1093-116.
PMID: 26161824
Introduction: Obesity is a rapidly expanding worldwide health problem. Various targets are investigated presently for the treatment of obesity, but there remains an unmet need for an effective drug therapy...
7.
Barmade M, Murumkar P, Sharma M, Shingala K, Giridhar R, Yadav M
Comb Chem High Throughput Screen
. 2014 Dec;
18(2):151-87.
PMID: 25543680
Among the various parasitic diseases, malaria is the deadliest one. Due to the emergence of high drug resistance to the existing drug candidates there is a global need for development...
8.
Miniyar P, Murumkar P, Patil P, Barmade M, Bothara K
Mini Rev Med Chem
. 2013 Apr;
13(11):1607-25.
PMID: 23544468
Pyrazine is one of the important class of heterocyclic compounds that can be obtained naturally or synthesized chemically. Pyrazine ring has got importance in exhibiting various biological activities in association...