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Magid Fallahi

Explore the profile of Magid Fallahi including associated specialties, affiliations and a list of published articles. Areas
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Articles 13
Citations 367
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Recent Articles
1.
Nakka K, Hachmer S, Mokhtari Z, Kovac R, Bandukwala H, Bernard C, et al.
Science . 2022 Aug; 377(6606):666-669. PMID: 35926054
Muscle stem cells (MuSCs) reside in a specialized niche that ensures their regenerative capacity. Although we know that innate immune cells infiltrate the niche in response to injury, it remains...
2.
Sun P, Watanabe K, Fallahi M, Lee B, Afetian M, Rheaume C, et al.
Proc Natl Acad Sci U S A . 2014 Jul; 111(28):10215-20. PMID: 24982158
Understanding the epigenetic mechanisms that control the activation of adult stem cells holds the promise of tissue and organ regeneration. Hair follicle stem cells have emerged as a prime model...
3.
Watanabe K, Villarreal-Ponce A, Sun P, Salmans M, Fallahi M, Andersen B, et al.
Dev Cell . 2014 Apr; 29(1):59-74. PMID: 24735879
Epithelial cells possess remarkable plasticity, having the ability to become mesenchymal cells through alterations in adhesion and motility (epithelial-to-mesenchymal transition [EMT]). However, how epithelial plasticity is kept in check in...
4.
Lee B, Villarreal-Ponce A, Fallahi M, Ovadia J, Sun P, Yu Q, et al.
Dev Cell . 2014 Apr; 29(1):47-58. PMID: 24735878
During epithelial tissue morphogenesis, developmental progenitor cells undergo dynamic adhesive and cytoskeletal remodeling to trigger proliferation and migration. Transcriptional mechanisms that restrict such a mild form of epithelial plasticity to...
5.
Gu B, Watanabe K, Sun P, Fallahi M, Dai X
Cell Stem Cell . 2013 May; 13(1):48-61. PMID: 23684539
Epigenetic mechanisms regulating lineage differentiation of mammary stem cells (MaSCs) remain poorly understood. Pygopus 2 (Pygo2) is a histone methylation reader and a context-dependent Wnt/β-catenin coactivator. Here we provide evidence...
6.
Cherkasov A, Ban F, Santos-Filho O, Thorsteinson N, Fallahi M, Hammond G
J Med Chem . 2008 Mar; 51(7):2047-56. PMID: 18330978
A benchmark data set of steroids with known affinity for sex hormone-binding globulin (SHBG) has been widely used to validate popular molecular field-based QSAR techniques. We have expanded the data...
7.
Schobert R, Bernhardt G, Biersack B, Bollwein S, Fallahi M, Grotemeier A, et al.
ChemMedChem . 2007 Feb; 2(3):333-42. PMID: 17266159
Esters of 6-aminomethylnicotinic acid with various steroidal alcohols were treated with K(2)PtCl(4) to give the N,N-chelated dichloroplatinum(II) complex conjugates 4. Their interaction with plasmid DNA was monitored by electrophoretic mobility...
8.
Cherkasov A, Ban F, Li Y, Fallahi M, Hammond G
J Med Chem . 2006 Dec; 49(25):7466-78. PMID: 17149875
A combination of protein-ligand docking and ligand-based QSAR approaches has been elaborated, aiming to speed-up the process of virtual screening. In particular, this approach utilizes docking scores generated for already...
9.
Cherkasov A, Shi Z, Li Y, Jones S, Fallahi M, Hammond G
J Chem Inf Model . 2005 Nov; 45(6):1842-53. PMID: 16309292
We have developed a novel iterative approach for calculation of partial charges in proteins within the framework of the 'molecular capacitance' model. The method operates by an effective 'inductive' electronegativity...
10.
Cherkasov A, Shi Z, Fallahi M, Hammond G
J Med Chem . 2005 Apr; 48(9):3203-13. PMID: 15857126
Using "in silico" drug design methodologies, we have discovered several nonsteroidal compounds of natural origin that bind to human sex hormone binding globulin (SHBG) with affinity constants of 0.1 x...