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Magdalena J Lorenowicz

Explore the profile of Magdalena J Lorenowicz including associated specialties, affiliations and a list of published articles. Areas
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Articles 19
Citations 8460
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Recent Articles
11.
de Groot R, Rappel S, Lorenowicz M, Korswagen H
Cell Signal . 2014 Sep; 26(12):2601-5. PMID: 25178265
Wnt proteins are lipid modified signaling molecules that have essential functions in development and adult tissue homeostasis. Secretion of Wnt is mediated by the transmembrane protein Wntless, which binds Wnt...
12.
Lorenowicz M, Macurkova M, Harterink M, Middelkoop T, de Groot R, Betist M, et al.
Cell Signal . 2013 Sep; 26(1):19-31. PMID: 24056045
Secretion of Wnt proteins is mediated by the Wnt sorting receptor Wls, which transports Wnt from the Golgi to the cell surface for release. To maintain efficient Wnt secretion, Wls...
13.
Harterink M, Port F, Lorenowicz M, McGough I, Silhankova M, Betist M, et al.
Nat Cell Biol . 2011 Jul; 13(8):914-923. PMID: 21725319
Wnt proteins are lipid-modified glycoproteins that play a central role in development, adult tissue homeostasis and disease. Secretion of Wnt proteins is mediated by the Wnt-binding protein Wntless (Wls), which...
14.
Lorenowicz M, Korswagen H
Exp Cell Res . 2009 Jun; 315(16):2683-9. PMID: 19559695
Wnt proteins are members of a highly conserved family of signalling molecules that play a central role in development and disease. During the past years, the different signalling pathways that...
15.
Lorenowicz M, Fernandez-Borja M, Kooistra M, Bos J, Hordijk P
Eur J Cell Biol . 2008 Jul; 87(10):779-92. PMID: 18635287
The vascular endothelium provides a semi-permeable barrier, which restricts the passage of fluid, macromolecules and cells to the surrounding tissues. Cyclic AMP promotes endothelial barrier function and protects the endothelium...
16.
Yang P, Lorenowicz M, Silhankova M, Coudreuse D, Betist M, Korswagen H
Dev Cell . 2007 Dec; 14(1):140-7. PMID: 18160347
Wnt proteins are secreted signaling molecules that play a central role in development and adult tissue homeostasis. We have previously shown that Wnt signaling requires retromer function in Wnt-producing cells....
17.
Lorenowicz M, Fernandez-Borja M, van Stalborch A, van Sterkenburg M, Hiemstra P, Hordijk P
Am J Physiol Lung Cell Mol Physiol . 2007 Sep; 293(5):L1321-31. PMID: 17827248
Cadherin-mediated cell-cell adhesion controls the morphology and function of epithelial cells and is a critical component of the pathology of chronic inflammatory disorders. Dynamic interactions between cadherins and the actin...
18.
Lorenowicz M, Fernandez-Borja M, Hordijk P
Arterioscler Thromb Vasc Biol . 2007 Mar; 27(5):1014-22. PMID: 17347487
The migration of leukocytes across the vascular endothelium is crucial for immunosurveillance as well as for inflammatory responses. Uncontrolled leukocyte transendothelial migration results in pathologies such as asthma, rheumatoid arthritis,...
19.
Lorenowicz M, van Gils J, de Boer M, Hordijk P, Fernandez-Borja M
J Leukoc Biol . 2006 Aug; 80(6):1542-52. PMID: 16940330
Extravasation of leukocytes is a crucial process in the immunological defense. In response to a local concentration of chemokines, circulating leukocytes adhere to and migrate across the vascular endothelium toward...