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Mads Gurtler

Explore the profile of Mads Gurtler including associated specialties, affiliations and a list of published articles. Areas
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Articles 7
Citations 1742
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Recent Articles
1.
Veres A, Faust A, Bushnell H, Engquist E, Kenty J, Harb G, et al.
Nature . 2019 May; 569(7756):368-373. PMID: 31068696
In vitro differentiation of human stem cells can produce pancreatic β-cells; the loss of this insulin-secreting cell type underlies type 1 diabetes. Here, as a step towards understanding this differentiation...
2.
Sharon N, Chawla R, Mueller J, Vanderhooft J, Whitehorn L, Rosenthal B, et al.
Cell . 2019 Jan; 176(4):790-804.e13. PMID: 30661759
The pancreatic islets of Langerhans regulate glucose homeostasis. The loss of insulin-producing β cells within islets results in diabetes, and islet transplantation from cadaveric donors can cure the disease. In ...
3.
Millman J, Xie C, Van Dervort A, Gurtler M, Pagliuca F, Melton D
Nat Commun . 2016 Aug; 7:12379. PMID: 27487970
No abstract available.
4.
Millman J, Xie C, Van Dervort A, Gurtler M, Pagliuca F, Melton D
Nat Commun . 2016 May; 7:11463. PMID: 27163171
We recently reported the scalable in vitro production of functional stem cell-derived β-cells (SC-β cells). Here we extend this approach to generate the first SC-β cells from type 1 diabetic...
5.
Vegas A, Veiseh O, Gurtler M, Millman J, Pagliuca F, Bader A, et al.
Nat Med . 2016 Apr; 22(4):446. PMID: 27050590
No abstract available.
6.
Vegas A, Veiseh O, Gurtler M, Millman J, Pagliuca F, Bader A, et al.
Nat Med . 2016 Jan; 22(3):306-11. PMID: 26808346
The transplantation of glucose-responsive, insulin-producing cells offers the potential for restoring glycemic control in individuals with diabetes. Pancreas transplantation and the infusion of cadaveric islets are currently implemented clinically, but...
7.
Pagliuca F, Millman J, Gurtler M, Segel M, Van Dervort A, Ryu J, et al.
Cell . 2014 Oct; 159(2):428-39. PMID: 25303535
The generation of insulin-producing pancreatic β cells from stem cells in vitro would provide an unprecedented cell source for drug discovery and cell transplantation therapy in diabetes. However, insulin-producing cells...