Maciej T Nogalski
Overview
Explore the profile of Maciej T Nogalski including associated specialties, affiliations and a list of published articles.
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17
Citations
640
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Recent Articles
1.
Naseri-Nosar P, Nogalski M, Shenk T
Proc Natl Acad Sci U S A
. 2021 Mar;
118(12).
PMID: 33723080
The tryptophan metabolite, kynurenine, is known to be produced at elevated levels within human cytomegalovirus (HCMV)-infected fibroblasts. Kynurenine is an endogenous aryl hydrocarbon receptor (AhR) ligand. Here we show that...
2.
Fulkerson H, Nogalski M, Collins-McMillen D, Yurochko A
Methods Mol Biol
. 2021 Feb;
2244:1-18.
PMID: 33555579
Human cytomegalovirus (HCMV) is a betaherpesvirus with a global seroprevalence of 60-90%. HCMV is the leading cause of congenital infections and poses a great health risk to immunocompromised individuals. Although...
3.
Nogalski M, Shenk T
Proc Natl Acad Sci U S A
. 2020 Dec;
117(50):31891-31901.
PMID: 33257565
Pericentromeric human satellite II (HSATII) repeats are normally silent but can be actively transcribed in tumor cells, where increased HSATII copy number is associated with a poor prognosis in colon...
4.
Chen S, Shenk T, Nogalski M
Proc Natl Acad Sci U S A
. 2019 Sep;
116(38):18971-18982.
PMID: 31481624
Human cytomegalovirus (HCMV) manipulates many aspects of host cell biology to create an intracellular milieu optimally supportive of its replication and spread. Our study reveals that levels of several components...
5.
Nogalski M, Solovyov A, Kulkarni A, Desai N, Oberstein A, Levine A, et al.
Nat Commun
. 2019 Jan;
10(1):90.
PMID: 30626867
Tandem satellite repeats account for 3% of the human genome. One of them, Human Satellite II (HSATII), is highly expressed in several epithelial cancers and cancer cell lines. Here we...
6.
Collins-McMillen D, Stevenson E, Kim J, Lee B, Cieply S, Nogalski M, et al.
J Virol
. 2017 Oct;
91(24).
PMID: 29021395
Human cytomegalovirus (HCMV) infects peripheral blood monocytes and triggers biological changes that promote viral dissemination and persistence. We have shown that HCMV induces a proinflammatory state in infected monocytes, resulting...
7.
Collins-McMillen D, Kim J, Nogalski M, Stevenson E, Chan G, Caskey J, et al.
J Virol
. 2015 Dec;
90(5):2356-71.
PMID: 26676786
Unlabelled: Monocytes play a key role in the hematogenous dissemination of human cytomegalovirus (HCMV) to target organ systems. To infect monocytes and reprogram them to deliver infectious virus, HCMV must...
8.
Nogalski M, Collins-McMillen D, Yurochko A
Methods Mol Biol
. 2014 Mar;
1119:15-28.
PMID: 24639215
Human cytomegalovirus (HCMV) is a human pathogen that infects greater than 50 % of the human population. HCMV infection is usually asymptomatic in most individuals. That is, primary infection or...
9.
Nogalski M, Chan G, Stevenson E, Collins-McMillen D, Yurochko A
PLoS Pathog
. 2013 Jul;
9(7):e1003463.
PMID: 23853586
We have established that HCMV acts as a specific ligand engaging and activating cellular integrins on monocytes. As a result, integrin signaling via Src activation leads to the functional activation...
10.
Nogalski M, Chan G, Stevenson E, Collins-McMillen D, Yurochko A
J Vis Exp
. 2012 Dec;
(70):e4165.
PMID: 23242175
Cellular motility is an important biological process for both unicellular and multicellular organisms. It is essential for movement of unicellular organisms towards a source of nutrients or away from unsuitable...