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Laura Marquez-Exposito

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Articles 27
Citations 534
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Recent Articles
1.
Rayego-Mateos S, Marquez-Exposito L, Basantes P, Tejedor-Santamaria L, Sanz A, Nguyen T, et al.
Antioxidants (Basel) . 2023 Aug; 12(8). PMID: 37627536
Inflammation is a key characteristic of both acute and chronic kidney diseases. Preclinical data suggest the involvement of the NLRP3/Inflammasome, receptor-interacting protein kinase-3 (RIPK3), and NRF2/oxidative pathways in the regulation...
2.
Martinelli R, Rayego-Mateos S, Alique M, Marquez-Exposito L, Tejedor-Santamaria L, Ortiz A, et al.
Nutrients . 2023 Mar; 15(6). PMID: 36986078
As life expectancy increases in many countries, the prevalence of age-related diseases also rises. Among these conditions, chronic kidney disease is predicted to become the second cause of death in...
3.
Trionfetti F, Marchant V, Gonzalez-Mateo G, Kawka E, Marquez-Exposito L, Ortiz A, et al.
Int J Mol Sci . 2023 Mar; 24(6). PMID: 36982834
Chronic kidney disease (CKD) incidence is growing worldwide, with a significant percentage of CKD patients reaching end-stage renal disease (ESRD) and requiring kidney replacement therapies (KRT). Peritoneal dialysis (PD) is...
4.
Rodrigues-Diez R, Tejera-Munoz A, Orejudo M, Marquez-Exposito L, Santos-Sanchez L, Rayego-Mateos S, et al.
Nefrologia (Engl Ed) . 2022 Sep; 41(3):244-257. PMID: 36166242
Interleukin-17A (IL-17A) is a proinflammatory cytokine produced by cells of the immune system, predominantly Th17 and γδ lymphocytes. In this paper, we review the role of IL-17A in the pathogenesis...
5.
Valentijn F, Knoppert S, Marquez-Exposito L, Rodrigues-Diez R, Pissas G, Tang J, et al.
Kidney Int . 2022 Aug; 102(6):1305-1319. PMID: 35921911
Chronic allograft dysfunction with progressive fibrosis of unknown cause remains a major issue after kidney transplantation, characterized by ischemia-reperfusion injury (IRI). One hypothesis to account for this is that spontaneous...
6.
Marquez-Exposito L, Lavoz C, Cantero-Navarro E, Rodrigues-Diez R, Mezzano S, Ruiz-Ortega M
Methods Mol Biol . 2022 Jun; 2472:187-196. PMID: 35674901
The NOTCH signaling pathway is an evolutionarily conserved family of transmembrane receptors, ligands, and transcription factors. The NOTCH signaling is activated in many biological processes including nephrogenesis, tubulogenesis, and glomerulogenesis,...
7.
Tejedor-Santamaria L, Morgado-Pascual J, Marquez-Exposito L, Suarez-Alvarez B, Rodrigues-Diez R, Tejera-Munoz A, et al.
Pharmaceuticals (Basel) . 2022 Feb; 15(2). PMID: 35215234
Crescentic glomerulonephritis is a devastating autoimmune disease that without early and properly treatment may rapidly progress to end-stage renal disease and death. Current immunosuppressive treatment provides limited efficacy and an...
8.
Rayego-Mateos S, Morgado-Pascual J, Lavoz C, Rodrigues-Diez R, Marquez-Exposito L, Tejera-Munoz A, et al.
Biomolecules . 2022 Feb; 12(2). PMID: 35204752
Cellular communication network-2 (CCN2), also called connective tissue growth factor (CTGF), is considered a fibrotic biomarker and has been suggested as a potential therapeutic target for kidney pathologies. CCN2 is...
9.
Marquez-Exposito L, Tejedor-Santamaria L, Valentijn F, Tejera-Munoz A, Rayego-Mateos S, Marchant V, et al.
Antioxidants (Basel) . 2022 Feb; 11(2). PMID: 35204184
Chronic kidney disease (CKD) can be considered as a clinical model for premature aging. However, non-invasive biomarkers to detect early kidney damage and the onset of a senescent phenotype are...
10.
Rayego-Mateos S, Marquez-Exposito L, Rodrigues-Diez R, Sanz A, Guiteras R, Dolade N, et al.
Int J Mol Sci . 2022 Feb; 23(3). PMID: 35163470
Chronic kidney disease (CKD) will become the fifth global cause of death by 2040, thus emphasizing the need to better understand the molecular mechanisms of damage and regeneration in the...