Maarten Hoogenkamp
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Explore the profile of Maarten Hoogenkamp including associated specialties, affiliations and a list of published articles.
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27
Citations
978
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Recent Articles
1.
Hantusch B, Kenner L, Stanulovic V, Hoogenkamp M, Brown G
Int J Mol Sci
. 2024 Sep;
25(17).
PMID: 39273194
The nuclear hormone family of receptors regulates gene expression. The androgen receptor (AR), upon ligand binding and homodimerization, shuttles from the cytosol into the nucleus to activate gene expression. Thyroid...
2.
Stanulovic V, Al Omair S, Reed M, Roberts J, Potluri S, Fulton-Ward T, et al.
Haematologica
. 2024 May;
109(11):3505-3519.
PMID: 38813748
T-cell acute lymphoblastic leukemia (T-ALL) is a cancer of the immune system. Approximately 20% of pediatric and 50% of adult T-ALL patients have refractory disease or relapse and die from...
3.
Zatyka M, Rosenstock T, Sun C, Palhegyi A, Hughes G, Lara-Reyna S, et al.
Stem Cell Reports
. 2023 May;
18(5):1090-1106.
PMID: 37163979
Mitochondrial dysfunction involving mitochondria-associated ER membrane (MAM) dysregulation is implicated in the pathogenesis of late-onset neurodegenerative diseases, but understanding is limited for rare early-onset conditions. Loss of the MAM-resident protein...
4.
Stanulovic V, Cauchy P, Assi S, Hoogenkamp M
Nucleic Acids Res
. 2017 Oct;
45(17):9874-9888.
PMID: 28973433
LMO2 is a bridging factor within a DNA binding complex and is required for definitive haematopoiesis to occur. The developmental stage of the block in haematopoietic specification is not known....
5.
Obier N, Cauchy P, Assi S, Gilmour J, Lie-A-Ling M, Lichtinger M, et al.
Development
. 2016 Nov;
143(23):4324-4340.
PMID: 27802171
The transmission of extracellular signals into the nucleus involves inducible transcription factors, but how different signalling pathways act in a cell type-specific fashion is poorly understood. Here, we studied the...
6.
Goode D, Obier N, Vijayabaskar M, Lie-A-Ling M, Lilly A, Hannah R, et al.
Dev Cell
. 2016 Mar;
36(5):572-87.
PMID: 26923725
Metazoan development involves the successive activation and silencing of specific gene expression programs and is driven by tissue-specific transcription factors programming the chromatin landscape. To understand how this process executes...
7.
van Oevelen C, Collombet S, Vicent G, Hoogenkamp M, Lepoivre C, Badeaux A, et al.
Stem Cell Reports
. 2015 Aug;
5(2):232-47.
PMID: 26235892
Transcription-factor-induced somatic cell conversions are highly relevant for both basic and clinical research yet their mechanism is not fully understood and it is unclear whether they reflect normal differentiation processes....
8.
Cauchy P, James S, Zacarias-Cabeza J, Ptasinska A, Imperato M, Assi S, et al.
Cell Rep
. 2015 Jul;
12(5):821-36.
PMID: 26212328
Acute myeloid leukemia (AML) is characterized by recurrent mutations that affect the epigenetic regulatory machinery and signaling molecules, leading to a block in hematopoietic differentiation. Constitutive signaling from mutated growth...
9.
Ptasinska A, Assi S, Martinez-Soria N, Imperato M, Piper J, Cauchy P, et al.
Cell Rep
. 2014 Sep;
8(6):1974-1988.
PMID: 25242324
Oncogenic transcription factors such as RUNX1/ETO, which is generated by the chromosomal translocation t(8;21), subvert normal blood cell development by impairing differentiation and driving malignant self-renewal. Here, we use digital...
10.
Zhang H, Alberich-Jorda M, Amabile G, Yang H, Staber P, Di Ruscio A, et al.
Cancer Cell
. 2013 Nov;
24(5):575-88.
PMID: 24183681
Mutation or epigenetic silencing of the transcription factor C/EBPα is observed in ∼10% of patients with acute myeloid leukemia (AML). In both cases, a common global gene expression profile is...