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Maarten A C Broeren

Explore the profile of Maarten A C Broeren including associated specialties, affiliations and a list of published articles. Areas
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Articles 43
Citations 316
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Recent Articles
1.
van den Wildenberg S, Genet S, Broeren M, van Dongen J, van den Oetelaar M, Brunsveld L, et al.
Anal Chem . 2024 Dec; 97(1):516-525. PMID: 39710932
Quantification of intact proteins in serum by liquid chromatography high-resolution mass spectrometry (HRMS) may be a useful alternative to bottom-up LC-MS or conventional ligand binding assays, due to reduced assay...
2.
Kerstens J, Schreurs M, de Vries J, Neuteboom R, Brenner J, Crijnen Y, et al.
Neurol Neuroimmunol Neuroinflamm . 2024 Oct; 11(6):e200318. PMID: 39467237
Background And Objectives: Autoimmune encephalitis (AIE) and paraneoplastic neurologic syndromes (PNSs) encompass a heterogeneous group of antibody-associated disorders. Both the number of syndromes and commercially available antibody tests have increased...
3.
Osinga J, Nelson S, Walsh J, Ashoor G, Palomaki G, Lopez-Bermejo A, et al.
J Clin Endocrinol Metab . 2024 Jul; 109(11):e2151-e2158. PMID: 39083675
Background: Establishing local trimester-specific reference intervals for gestational TSH and free T4 (FT4) is often not feasible, necessitating alternative strategies. We aimed to systematically quantify the diagnostic performance of standardized...
4.
van den Wildenberg S, Genet S, Streng A, Broeren M, Deenen M, van Dongen J, et al.
J Pharm Biomed Anal . 2024 Jul; 249:116381. PMID: 39067280
Fluorouracil is among the most used antimetabolite drugs for the chemotherapeutic treatment of various types of gastrointestinal malignancies. Dihydropyrimidine dehydrogenase (DPYD) genotyping prior to fluorouracil treatment is considered standard practice...
5.
van den Wildenberg S, Genet S, Broeren M, van Dongen J, Brunsveld L, Scharnhorst V, et al.
J Proteome Res . 2024 Jul; 23(8):3726-3730. PMID: 39013105
Intact-mass spectrometry has huge potential for clinical application, as it enables both quantitative and qualitative analysis of intact proteins and possibly unlocks additional pathophysiological information via, e.g., detection of specific...
6.
Broekhuis A, Koenen S, Broeren M, Krabbe J, Pop V
Acta Obstet Gynecol Scand . 2024 Apr; 103(7):1437-1443. PMID: 38650165
Introduction: A considerable amount of neonatal morbidity and mortality worldwide is caused by preterm birth. To date, the underlying etiology of preterm birth has not been fully clarified. Previous studies...
7.
Osinga J, Liu Y, MaNnisto T, Vafeiadi M, Tao F, Vaidya B, et al.
Thyroid . 2024 Mar; 34(5):646-658. PMID: 38546971
International guidelines recommend targeted screening to identify gestational thyroid dysfunction. However, currently used risk factors have questionable discriminative ability. We quantified the risk for thyroid function test abnormalities for a...
8.
Zhang Y, Mustieles V, Korevaar T, Martin L, Sun Y, Bibi Z, et al.
Environ Pollut . 2024 Feb; 346:123513. PMID: 38350534
Per- and polyfluoroalkyl substances (PFAS) exposure was associated with changes in thyroid function in pregnant mothers and the general population. Limited such evidence exists in other susceptible populations such as...
9.
Genet S, Visser E, Youssef-El Soud M, Belderbos H, Stege G, de Saegher M, et al.
Lung Cancer . 2024 Jan; 189:107477. PMID: 38271919
Objectives: Timely diagnosis of lung cancer (LC) is crucial to achieve optimal patient care and outcome. Moreover, the number of procedures required to obtain a definitive diagnosis can have a...
10.
van Aalen E, de Vries I, Hanckmann E, Stevens J, Romagnoli T, Derijks L, et al.
Sens Diagn . 2023 Nov; 2(6):1492-1500. PMID: 38013761
Therapeutic drug monitoring (TDM) of tumor necrosis factor-α (TNFα)-inhibitors adalimumab and infliximab is important to establish optimal drug dose and maximize treatment efficacy. Currently, TDM is primarily performed with ELISA...