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Daan van de Kerkhof

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Articles 41
Citations 245
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Recent Articles
1.
Hanrath M, Banken E, van den Wildenberg S, van de Kerkhof D, Moes D, Boisdron-Celle M, et al.
Cancer Chemother Pharmacol . 2025 Feb; 95(1):34. PMID: 39955449
Purpose: In 20-30% of the patients, fluoropyrimidines (5-FU) based chemotherapy leads to severe toxicity, which is associated with dihydropyridine dehydrogenase (DPD) deficiency. Therefore, DPYD genotyping became standard practice before treatment...
2.
Adelaars S, Lapre C, Raaijmakers P, Konings C, Mischi M, Arthur Bouwman R, et al.
J Chromatogr B Analyt Technol Biomed Life Sci . 2025 Jan; 1252:124444. PMID: 39761609
Monitoring of kidney function traditionally relies on plasma creatinine concentrations, necessitating invasive blood draws. Non-invasively obtainable biofluids, such as sweat and saliva, present a patient-friendly alternative with potential for continuous...
3.
van den Wildenberg S, Genet S, Broeren M, van Dongen J, van den Oetelaar M, Brunsveld L, et al.
Anal Chem . 2024 Dec; 97(1):516-525. PMID: 39710932
Quantification of intact proteins in serum by liquid chromatography high-resolution mass spectrometry (HRMS) may be a useful alternative to bottom-up LC-MS or conventional ligand binding assays, due to reduced assay...
4.
van den Wildenberg S, Genet S, Streng A, Broeren M, Deenen M, van Dongen J, et al.
J Pharm Biomed Anal . 2024 Jul; 249:116381. PMID: 39067280
Fluorouracil is among the most used antimetabolite drugs for the chemotherapeutic treatment of various types of gastrointestinal malignancies. Dihydropyrimidine dehydrogenase (DPYD) genotyping prior to fluorouracil treatment is considered standard practice...
5.
van den Wildenberg S, Genet S, Broeren M, van Dongen J, Brunsveld L, Scharnhorst V, et al.
J Proteome Res . 2024 Jul; 23(8):3726-3730. PMID: 39013105
Intact-mass spectrometry has huge potential for clinical application, as it enables both quantitative and qualitative analysis of intact proteins and possibly unlocks additional pathophysiological information via, e.g., detection of specific...
6.
Oud J, de Haas M, de Vooght K, van de Kerkhof D, Som N, Pequeriaux N, et al.
Br J Haematol . 2024 Mar; 204(5):2103-2111. PMID: 38494337
Red blood cell autoimmunity and alloimmunity are potentially linked. Quantification of this association can tailor extensively matched red blood cell transfusions in patients with autoimmunity. Using an incident new-user cohort...
7.
Valk S, Caram-Deelder C, Groenwold R, Evers D, de Vooght K, van de Kerkhof D, et al.
Haematologica . 2024 Feb; 109(8):2478-2486. PMID: 38385259
Previous studies found exposure to red blood cell transfusions from female donors who have been pregnant reduces survival in male patients compared to exposure to male donor products, but evidence...
8.
Genet S, Visser E, Youssef-El Soud M, Belderbos H, Stege G, de Saegher M, et al.
Lung Cancer . 2024 Jan; 189:107477. PMID: 38271919
Objectives: Timely diagnosis of lung cancer (LC) is crucial to achieve optimal patient care and outcome. Moreover, the number of procedures required to obtain a definitive diagnosis can have a...
9.
Adelaars S, Konings C, Cox L, Boonen E, Mischi M, Arthur Bouwman R, et al.
Clin Chem Lab Med . 2024 Jan; 62(6):1118-1125. PMID: 38253354
Objectives: Urea and creatinine concentrations in plasma are used to guide hemodialysis (HD) in patients with end-stage renal disease (ESRD). To support individualized HD treatment in a home situation, there...
10.
Poel T, de Rouw N, Pequeriaux N, van de Kerkhof D, Windsant A, van Marum R, et al.
Hemodial Int . 2023 Nov; 28(1):72-76. PMID: 37962053
Purpose: Apixaban is a factor Xa inhibitor used in patients undergoing hemodialysis treatment. The objective of this study is to investigate the effect of hemodialysis on apixaban plasma concentrations. Methods:...