M Weigert
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Explore the profile of M Weigert including associated specialties, affiliations and a list of published articles.
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174
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3739
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Recent Articles
11.
Brard F, Shannon M, Prak E, Litwin S, Weigert M
J Exp Med
. 1999 Sep;
190(5):691-704.
PMID: 10477553
Antibodies to single-stranded (ss)DNA are expressed in patients with systemic lupus erythematosus and in lupus-prone mouse models such as the MRL/Mp-lpr/lpr (MRL/lpr) strain. In nonautoimmune mice, B cells bearing immunoglobulin...
12.
Weigert M, Hofstetter G, Kaipl D, Gottlich H, Krischker U, Bichler K, et al.
J Assist Reprod Genet
. 1999 Jul;
16(6):287-93.
PMID: 10394523
Purpose: The aim of the present study was to investigate the influence of smoking on different parameters such as oocyte count, embryo score, and basal hormone values within the scope...
13.
Xu H, Li H, Suri-Payer E, Hardy R, Weigert M
J Exp Med
. 1998 Oct;
188(7):1247-54.
PMID: 9763604
Anti-DNA antibodies are regulated in normal individuals but are found in high concentration in the serum of systemic lupus erythematosus (SLE) patients and the MRL lpr/lpr mouse model of SLE....
14.
Stewart J, Lee C, Ibrahim S, Watts P, Shlomchik M, Weigert M, et al.
Mol Immunol
. 1998 Mar;
34(15):1067-82.
PMID: 9519765
In 1970, before any antigen-bound immunoglobulin structure had been solved, Elvin Kabat proposed that regions of high amino acid diversity would be the antigen binding sites of immunoglobulin (Kabat, 1970)....
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16.
Stewart J, Agosto H, Litwin S, Welsh J, Shlomchik M, Weigert M, et al.
J Immunol
. 1997 Aug;
159(4):1728-38.
PMID: 9257834
Rheumatoid factors (RF) associated with arthritic joint erosion are only seen transiently, if at all, in nondiseased individuals. Therefore, a tolerance mechanism must exist that prevents pathologic RF B cells...
17.
Chen C, Prak E, Weigert M
Immunity
. 1997 Jan;
6(1):97-105.
PMID: 9052841
We have generated site-directed transgenic mice whose transgenes code for anti-DNA antibodies. These antibodies are representative of the lupus-associated anti-DNAs seen in mouse models of autoimmunity and human SLE, and...
18.
Chen C, Nagy Z, Prak E, Weigert M
Immunity
. 1995 Dec;
3(6):747-55.
PMID: 8777720
We have generated a site-directed transgenic (sd-tg) mouse model in which the JH locus has been replaced with a rearranged VDJ coding for the heavy chain of an anti-DNA antibody....
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20.
Ibrahim S, Weigert M, Basu C, Erikson J, Radic M
J Immunol
. 1995 Sep;
155(6):3223-33.
PMID: 7673735
We studied mice expressing one of two H chain transgenes. Both transgenes expressed the same 3H9 anti-DNA VDJ, but differed in their constant domains. The IgM transgene efficiently induced tolerance...