M Tschernutter
Overview
Explore the profile of M Tschernutter including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
292
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0
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Recent Articles
1.
Georgiadis A, Tschernutter M, Bainbridge J, Robbie S, McIntosh J, Nathwani A, et al.
Gene Ther
. 2009 Dec;
17(4):486-93.
PMID: 20010626
Gene therapy for inherited retinal degeneration in which expression of a mutant allele has a gain-of-function effect on photoreceptor cells is likely to depend on efficient silencing of the mutated...
2.
West E, Pearson R, Tschernutter M, Sowden J, MacLaren R, Ali R
Exp Eye Res
. 2008 Feb;
86(4):601-11.
PMID: 18294631
Retinal degeneration is the leading cause of untreatable blindness in the developed world. Cell transplantation strategies provide a novel therapeutic approach to repair the retina and restore sight. Previously, we...
3.
Tschernutter M, Jenkins S, Waseem N, Saihan Z, Holder G, Bird A, et al.
Br J Ophthalmol
. 2006 May;
90(6):718-23.
PMID: 16714263
Background/aim: MERTK, a tyrosine kinase receptor protein expressed by the retinal pigment epithelium (RPE), is mutated in both rodent models and humans affected by retinal disease. This study reports a...
4.
Balaggan K, Binley K, Esapa M, Iqball S, Askham Z, Kan O, et al.
J Gene Med
. 2005 Nov;
8(3):275-85.
PMID: 16299834
Background: We have developed minimal non-primate lentiviral vectors based on the equine infectious anaemia virus (EIAV). We evaluated the in vivo expression profiles of these vectors delivered regionally to ocular...
5.
Tschernutter M, Schlichtenbrede F, Howe S, Balaggan K, Munro P, Bainbridge J, et al.
Gene Ther
. 2005 Jan;
12(8):694-701.
PMID: 15660111
The Royal College of Surgeons (RCS) rat is a well-characterized model of autosomal recessive retinitis pigmentosa (RP) due to a defect in the retinal pigment epithelium (RPE). It is homozygous...
6.
Schlichtenbrede F, MacNeil A, Bainbridge J, Tschernutter M, Thrasher A, Smith A, et al.
Gene Ther
. 2003 Mar;
10(6):523-7.
PMID: 12621456
Intraocular delivery of a variety of neurotrophic factors has been widely investigated as a potential treatment for retinal dystrophy (RD). The most commonly studied factor, ciliary neurotrophic factor (CNTF), has...