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M Stookey

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Articles 6
Citations 87
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1.
Colbaugh P, Stookey M, Draper R
J Cell Biol . 1989 Jun; 108(6):2211-9. PMID: 2525560
We describe here the properties of a mutant of Chinese hamster ovary cells that expresses a conditional-lethal mutation affecting dense lysosomes. This mutant, termed V.24.1, is a member of the...
2.
Colbaugh P, Kao C, Shia S, Stookey M, Draper R
Somat Cell Mol Genet . 1988 Sep; 14(5):499-507. PMID: 3175766
We describe here the results of complementation studies with six mutant Chinese hamster ovary cells expressing temperature-sensitive lesions affecting the endocytic pathway. The mutants were crossed with representatives of the...
3.
Marnell M, Mathis L, Stookey M, Shia S, Stone D, Draper R
J Cell Biol . 1984 Dec; 99(6):1907-16. PMID: 6501408
We describe a mutant derived from Chinese hamster ovary cells that is offt-sensitive for viability and for resistance to certain protein toxins. This mutant, termed G.7.1, grows normally at 34...
4.
Draper R, OKeefe D, Stookey M, Graves J
J Biol Chem . 1984 Apr; 259(7):4083-8. PMID: 6706992
Modeccin is a toxic lectin that arrests protein synthesis in mammalian cells by catalytically inactivating 60 S ribosomes. To interact with 60 S ribosomes, the catalytic subunit of modeccin must...
5.
Marnell M, Shia S, Stookey M, Draper R
Infect Immun . 1984 Apr; 44(1):145-50. PMID: 6706404
To kill mammalian cells, diphtheria toxin must be endocytosed and encounter a low pH within intracellular vesicles. The low pH initiates penetration of the catalytically active A fragment of the...
6.
Marnell M, Stookey M, Draper R
J Cell Biol . 1982 Apr; 93(1):57-62. PMID: 7068760
Lysosomotropic amines are believed to inhibit the transport of diphtheria toxin to the cell cytoplasm by raising the pH within intracellular vesicles. If so, then other drugs that dissipate intracellular...