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M Shichiri

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Articles 308
Citations 2961
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Recent Articles
11.
Biwa T, Sakai M, Shichiri M, Horiuchi S
J Atheroscler Thromb . 2001 Jun; 7(1):14-20. PMID: 11425039
We and other groups have recently demonstrated that oxidized low density lipoprotein (Ox-LDL) induces proliferation of macrophages in vitro. Since previous immunohistochemical studies demonstrated that macrophages and macrophage derived foam...
12.
Oyadomari S, Gotoh T, Aoyagi K, Araki E, Shichiri M, Mori M
Nitric Oxide . 2001 Jun; 5(3):252-60. PMID: 11384198
Decreased availability of arginine and impaired production of NO (nitric oxide) have been implicated in the development of endothelial dysfunction. Citrulline formed by the NOS reaction is recycled to arginine...
13.
Ishimaru S, Shichiri M, Mineshita S, Hirata Y
Hypertens Res . 2001 Apr; 24(2):119-26. PMID: 11325070
Endothelin (ET)-1, a potent vasoconstrictor peptide derived from the endothelium, is markedly increased in endotoxic shock, although the pathophysiological role of ET-1 under septic conditions remains obscure. To delineate the...
14.
Shichiri M, Hirata Y
FASEB J . 2001 Apr; 15(6):1044-53. PMID: 11292666
Endostatin is a potent endogenous angiogenesis inhibitor that induces regression of tumors in mice. Neither an extracellular receptor for endostatin nor intracellular signals that result in the regression of tumor...
15.
Shiigai T, Shichiri M
Am J Kidney Dis . 2001 Mar; 37(3):477-83. PMID: 11228170
Angiotensin-converting enzyme (ACE) inhibitors exert a renoprotective effect in both diabetic and nondiabetic renal disease with variable efficacy. Proteinuric patients with nondiabetic renal disease, normotension, and restricted protein and sodium...
16.
Yoshizato K, Shirotani T, Furukawa N, Taguchi T, Motoshima H, Toyonaga T, et al.
Biochem Biophys Res Commun . 2001 Feb; 280(2):428-34. PMID: 11162534
The liver is a major target organ of insulin and is important for glucose homeostasis. We analyzed the tissue specific regulation of the insulin receptor gene in the liver by...
17.
Iwasaki H, Shichiri M, Marumo F, Hirata Y
Endocrinology . 2001 Feb; 142(2):564-72. PMID: 11159826
A novel vasodilator peptide, adrenomedullin (AM) stimulates extracellular signal-regulated kinase (ERK) 1/2 via yet uncharacterized 120 kDa tyrosine kinase(s) in rat vascular smooth muscle cells (VSMC). In the present study,...
18.
Doi M, Shichiri M, Katsuyama K, Marumo F, Hirata Y
Hypertens Res . 2000 Dec; 23(6):659-67. PMID: 11131279
Recent evidence suggests the possible involvement of inducible nitric oxide synthase (iNOS) in the development and maintenance of hypertension in certain animal models. Inflammatory cytokines activate nuclear factor (NF)-kappaB, which...
19.
Doi M, Shichiri M, Yoshida M, Marumo F, Hirata Y
Hypertens Res . 2000 Dec; 23(6):643-9. PMID: 11131277
Both integrins and endothelins (ETs) are known to play important roles in vascular remodeling via proliferation, apoptosis, and migration of vascular smooth muscle cells (VSMCs), whose dysfunctions have been implicated...
20.
Ohta K, Shichiri M, Kameya T, Matsubara O, Imai T, Marumo F, et al.
Endocr J . 2000 Nov; 47(4):487-92. PMID: 11075732
A 26 year-old man with suspected Cushing's disease underwent transsphenoidal exploration of the pituitary without any evidence of microadenoma or hyperplasia. Progressive hypercortisolism necessitated bilateral adrenalectomy. Postoperatively, skin pigmentation gradually...