M Porotto
Overview
Explore the profile of M Porotto including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
359
Followers
0
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Recent Articles
1.
Marcink T, Yariv E, Rybkina K, Mas V, Bovier F, Georges A, et al.
mBio
. 2020 Feb;
11(1).
PMID: 32047132
The receptor binding protein of parainfluenza virus, hemagglutinin-neuraminidase (HN), is responsible for actively triggering the viral fusion protein (F) to undergo a conformational change leading to insertion into the target...
2.
Porotto M, Ferren M, Chen Y, Siu Y, Makhsous N, Rima B, et al.
mBio
. 2019 May;
10(3).
PMID: 31064833
Infectious viruses so precisely fit their hosts that the study of natural viral infection depends on host-specific mechanisms that affect viral infection. For human parainfluenza virus 3, a prevalent cause...
3.
Bottom-Tanzer S, Rybkina K, Bell J, Alabi C, Mathieu C, Lu M, et al.
mBio
. 2019 Feb;
10(1).
PMID: 30782664
Paramyxoviruses, specifically, the childhood pathogen human parainfluenza virus type 3, are internalized into host cells following fusion between the viral and target cell membranes. The receptor binding protein, hemagglutinin (HA)-neuraminidase...
4.
Figueira T, Augusto M, Rybkina K, Stelitano D, Noval M, Harder O, et al.
Bioconjug Chem
. 2018 Sep;
29(10):3362-3376.
PMID: 30169965
The impact of influenza virus infection is felt each year on a global scale when approximately 5-10% of adults and 20-30% of children globally are infected. While vaccination is the...
5.
Figueira T, Palermo L, Veiga A, Huey D, Alabi C, Santos N, et al.
J Virol
. 2016 Oct;
91(1).
PMID: 27733647
Importance: Measles virus (MV) infection causes an acute illness that may be associated with infection of the central nervous system (CNS) and severe neurological disease. No specific treatment is available....
6.
Mathieu C, Huey D, Jurgens E, Welsch J, DeVito I, Talekar A, et al.
J Virol
. 2014 Nov;
89(2):1143-55.
PMID: 25378493
Unlabelled: Measles virus (MV) infection is undergoing resurgence and remains one of the leading causes of death among young children worldwide despite the availability of an effective measles vaccine. MV...
7.
Porotto M, Carta P, Deng Y, Kellogg G, Whitt M, Lu M, et al.
J Virol
. 2007 Jul;
81(19):10567-74.
PMID: 17652384
Hendra virus (HeV) and Nipah virus (NiV) constitute the Henipavirus genus of paramyxoviruses, both fatal in humans and with the potential for subversion as agents of bioterrorism. Binding of the...
8.
Porotto M, Doctor L, Carta P, Fornabaio M, Greengard O, Kellogg G, et al.
J Virol
. 2006 Sep;
80(19):9837-49.
PMID: 16973588
Hendra virus (HeV) is a recently identified paramyxovirus that is fatal in humans and could be used as an agent of bioterrorism. The HeV receptor-binding protein (G) is required in...
9.
Porotto M, Greengard O, Poltoratskaia N, Horga M, Moscona A
J Virol
. 2001 Jul;
75(16):7481-8.
PMID: 11462020
The envelope of human parainfluenza virus type 3 (HPF3) contains two viral glycoproteins, the hemagglutinin-neuraminidase (HN) and the fusion protein (F). HN, which is responsible for receptor attachment and for...
10.
Murrell M, Porotto M, Greengard O, Poltoratskaia N, Moscona A
J Virol
. 2001 Jun;
75(14):6310-20.
PMID: 11413297
Entry and fusion of human parainfluenza virus type 3 (HPF3) requires interaction of the viral hemagglutinin-neuraminidase (HN) glycoprotein with its sialic acid receptor. 4-Guanidino-2,4-dideoxy-2,3-dehydro-N-acetylneuraminic acid (4-GU-DANA; zanamivir), a sialic acid...