M P Byrne
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Explore the profile of M P Byrne including associated specialties, affiliations and a list of published articles.
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Articles
27
Citations
225
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Recent Articles
1.
Xenon tracers for cost effective laser induced fluorescence of alternative propellant Hall thrusters
Simmonds J, Byrne M, Chaplin V
Rev Sci Instrum
. 2024 Feb;
95(2).
PMID: 38341718
One of the limiting factors to developing plasma thrusters on alternative propellants is the cost associated with changing the diagnostic tools, which are often propellant-dependent. For laser induced fluorescence (LIF),...
2.
Holder J, Bennett A, Chen J, Spencer D, Byrne M, Stites W
Biochemistry
. 2001 Nov;
40(46):13998-4003.
PMID: 11705391
To examine the importance of side chain packing to protein stability, each of the 11 leucines in staphylococcal nuclease was substituted with isoleucine and valine. The nine valines were substituted...
3.
Ahmed S, Byrne M, Jensen M, Hines H, Brueggemann E, Smith L
J Protein Chem
. 2001 Sep;
20(3):221-31.
PMID: 11565902
Highly purified recombinant zinc-endopeptidase light chain of the botulinum neurotoxin serotype A underwent autocatalytic proteolytic processing and fragmentation. In the absence of added zinc, initially 10-28 residues were cleaved from...
4.
Byrne M, Smith L
Biochimie
. 2000 Nov;
82(9-10):955-66.
PMID: 11086225
Botulism is a potentially lethal disease caused by one of seven homologous neurotoxic proteins usually produced by the bacterium, Clostridium botulinum. This neuromuscular disorder occurs through an exquisite series of...
5.
Byrne M, Titball R, Holley J, Smith L
Protein Expr Purif
. 2000 Mar;
18(3):327-37.
PMID: 10733887
A recombinant vaccine candidate was developed that protected mice against botulinum neurotoxin serotype F (BoNTF) intoxication. A synthetic gene encoding BoNTF fragment C (rBoNTF(H(c))) was designed, constructed, and inserted into...
6.
Hyser M, Chaudhry V, Byrne M
Am Surg
. 1999 Jul;
65(7):606-9; discussion 610.
PMID: 10399967
Our objective was to review our community hospital experience with laparoscopic management of choledocholithiasis from 1991 to 1997. We performed a retrospective review of all case records of patients with...
7.
Byrne M, Smith T, Montgomery V, Smith L
Infect Immun
. 1998 Sep;
66(10):4817-22.
PMID: 9746584
Recombinant botulinum neurotoxin serotype A binding domain [BoNT/A(Hc)], expressed in Pichia pastoris, was developed as a vaccine candidate for preventing botulinum neurotoxin type A (BoNT/A) intoxication. After fermentation and cell...
8.
Byrne M, Broomfield C, Stites W
J Protein Chem
. 1996 Feb;
15(2):131-6.
PMID: 8924198
Mustard gas, bis(2-chloroethyl)sulfide, treatment of proteins is shown to generate significant amounts of covalently crosslinked protein dimers. This is due to the preferential alkylation of cysteine residues. Crosslinking does not...
9.
Byrne M, Stites W
Protein Sci
. 1995 Dec;
4(12):2545-58.
PMID: 8580845
Nine single substitution cysteine mutants of staphylococcal nuclease (nuclease) were preferentially crosslinked at the introduced cysteine residues using three different bifunctional crosslinking reagents; 1,6-bismaleimidohexane (BMH), 1,3-dibromo-2-propanol (DBP), and the chemical...
10.
Byrne M, Manuel R, Lowe L, Stites W
Biochemistry
. 1995 Oct;
34(42):13949-60.
PMID: 7577991
Hydrogen bonds are a ubiquitous feature of protein structures, yet there is great uncertainty about the energetic contribution of hydrogen bonding to protein stability. This study addresses this question by...