M Norin
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Explore the profile of M Norin including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
142
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Recent Articles
1.
Hojjat-Farsangi M, Daneshmanesh A, Khan A, Shetye J, Mozaffari F, Kharaziha P, et al.
Leukemia
. 2018 May;
32(10):2291-2295.
PMID: 29725030
No abstract available.
2.
Norin M, Sundstrom M
Curr Opin Drug Discov Devel
. 2001 Sep;
4(3):284-90.
PMID: 11560059
Over the last few years, the utilization of protein structural information in drug discovery research has matured and is today applied throughout the process, ranging from genomics-derived target identification and...
3.
Morner A, Achour A, Norin M, Thorstensson R, Bjorling E
Virus Res
. 2000 Jun;
59(1):49-60.
PMID: 10854165
We have previously identified two distinct antigenic sites in the third variable region (V3) of human immunodeficiency virus type 2 (HIV-2) corresponding to the principal neutralizing determinant (PND) of HIV-1,...
4.
Skott P, Achour A, Norin M, Thorstensson R, Bjorling E
Viral Immunol
. 1999 May;
12(1):79-88.
PMID: 10333245
Several determinants of human immunodeficiency virus (HIV) have been suggested to harbor sites important for neutralization. The third variable region (V3) of the envelope glycoprotein (gp) is an important neutralizing...
5.
Hydrophobicity engineering of cholera toxin A1 subunit in the strong adjuvant fusion protein CTA1-DD
Agren L, Norin M, Lycke N, Lowenadler B
Protein Eng
. 1999 Apr;
12(2):173-8.
PMID: 10195289
Protein engineering of the cholera toxin A1 subunit (CTA1) fused to a dimer of the Ig-binding D-region of Staphylococcus aureus protein A (DD) was employed to investigate the effect of...
6.
Forsberg G, Forsgren M, Jaki M, Norin M, Sterky C, Enhorning A, et al.
J Biol Chem
. 1997 May;
272(19):12430-6.
PMID: 9139690
The monoclonal antibody 5T4, directed against a human tumor-associated antigen, was expressed as a secreted Fab superantigen fusion protein in Escherichia coli. The product is a putative agent for immunotherapy...
7.
Uppenberg J, Ohrner N, Norin M, Hult K, Kleywegt G, Patkar S, et al.
Biochemistry
. 1995 Dec;
34(51):16838-51.
PMID: 8527460
Many lipases are potent catalysts of stereoselective reactions and are therefore of interest for use in chemical synthesis. The crystal structures of lipases show a large variation in the shapes...
8.
Norin M, Haeffner F, Achour A, Norin T, Hult K
Protein Sci
. 1994 Sep;
3(9):1493-503.
PMID: 7833809
The substrate-binding sites of the triacyl glyceride lipases from Rhizomucor miehei, Humicola lanuginosa, and Candida rugosa were studied by means of computer modeling methods. The space around the active site...
9.
Norin M, Haeffner F, Hult K, Edholm O
Biophys J
. 1994 Aug;
67(2):548-59.
PMID: 7948673
We report on molecular dynamics simulations of a medium-sized protein, a lipase from Rhizomucor miehei, in vacuum, in water, and in a nonpolar solvent, methyl hexanoate. Depending on force field...
10.
Norin M, Olsen O, Svendsen A, Edholm O, Hult K
Protein Eng
. 1993 Nov;
6(8):855-63.
PMID: 8309933
Computational methods have been used to study the extensive conformational change of Rhizomucor miehei lipase upon activation. The present study considers the possible activation route, the energies involved and molecular...