M Mark Taketo
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Explore the profile of M Mark Taketo including associated specialties, affiliations and a list of published articles.
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52
Citations
1570
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Recent Articles
1.
Sun Q, Lee W, Hu H, Ogawa T, De Leon S, Katehis I, et al.
Nature
. 2023 Apr;
616(7958):774-782.
PMID: 37076619
For unknow reasons, the melanocyte stem cell (McSC) system fails earlier than other adult stem cell populations, which leads to hair greying in most humans and mice. Current dogma states...
2.
Cosgun K, Jumaa H, Robinson M, Kistner K, Xu L, Xiao G, et al.
bioRxiv
. 2023 Mar;
PMID: 36993619
Highlights: Unlike other cell lineages, B-cells express nuclear β-catenin protein at low baseline levels and depend on GSK3β for its degradation.In B-cells, β-catenin forms unique complexes with lymphoid-specific Ikaros factors...
3.
Qu R, Gupta K, Dong D, Jiang Y, Landa B, Saez C, et al.
Dev Cell
. 2022 Apr;
57(8):1053-1067.e5.
PMID: 35421372
Organ formation requires integrating signals to coordinate proliferation, specify cell fates, and shape tissue. Tracing these events and signals remains a challenge, as intermediate states across many critical transitions are...
4.
Goktuna S, Canli O, Bollrath J, Fingerle A, Horst D, Diamanti M, et al.
Cell Rep
. 2022 Mar;
38(9):110471.
PMID: 35235803
No abstract available.
5.
Parichha A, Suresh V, Chatterjee M, Kshirsagar A, Ben-Reuven L, Olender T, et al.
Nat Commun
. 2022 Feb;
13(1):633.
PMID: 35110543
The choroid plexus secretes cerebrospinal fluid and is critical for the development and function of the brain. In the telencephalon, the choroid plexus epithelium arises from the Wnt- expressing cortical...
6.
Hanada K, Kawada K, Nishikawa G, Toda K, Maekawa H, Nishikawa Y, et al.
Cancer Lett
. 2021 Sep;
522:129-141.
PMID: 34543685
Mutations of KRAS gene are found in various types of cancer, including colorectal cancer (CRC). Despite intense efforts, no pharmacological approaches are expected to be effective against KRAS-mutant cancers. Macropinocytosis...
7.
Ito T, Kawai Y, Yasui Y, Iriguchi S, Minagawa A, Ishii T, et al.
Commun Biol
. 2021 Jun;
4(1):694.
PMID: 34099861
Tumor-infiltrating lymphocytes (TIL), which include tumor-specific T lymphocytes with frequency, are used for adoptive cell transfer therapy (ACT) in clinical practice. The optimization of TIL preparation has been investigated to...
8.
Zhu B, Wu Y, Huang S, Zhang R, Son Y, Li C, et al.
Immunity
. 2021 May;
54(6):1200-1218.e9.
PMID: 33951416
Tissue macrophages self-renew during homeostasis and produce inflammatory mediators upon microbial infection. We examined the relationship between proliferative and inflammatory properties of tissue macrophages by defining the impact of the...
9.
Itatani Y, Yamamoto T, Zhong C, Molinolo A, Ruppel J, Hegde P, et al.
Proc Natl Acad Sci U S A
. 2020 Aug;
117(35):21598-21608.
PMID: 32817421
We tested and mice, which recapitulate key genetic abnormalities accumulating during colorectal cancer (CRC) tumorigenesis in humans, for responsiveness to anti-VEGF therapy. We found that even tumors in mice, although...
10.
Yamamoto T, Miyoshi H, Kakizaki F, Maekawa H, Yamaura T, Morimoto T, et al.
Cancers (Basel)
. 2020 Jul;
12(8).
PMID: 32708005
Some colorectal cancer patients harboring (fibroblast growth factor receptor) genetic alterations, such as copy number gain, mutation, and/or mRNA overexpression, were selected for enrollment in several recent clinical trials of...