M M Knight
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Explore the profile of M M Knight including associated specialties, affiliations and a list of published articles.
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62
Citations
1082
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Recent Articles
1.
Meng H, Fu S, Ferreira M, Hou Y, Pearce O, Gavara N, et al.
Osteoarthritis Cartilage
. 2022 Nov;
31(5):600-612.
PMID: 36368426
Objective: To clarify the role of YAP in modulating cartilage inflammation and degradation and the involvement of primary cilia and associated intraflagellar transport (IFT). Methods: Isolated primary chondrocytes were cultured...
2.
Fu S, Meng H, Inamdar S, Das B, Gupta H, Wang W, et al.
Osteoarthritis Cartilage
. 2021 Jan;
29(1):89-99.
PMID: 33395574
Objective: Cartilage health is maintained in response to a range of mechanical stimuli including compressive, shear and tensile strains and associated alterations in osmolality. The osmotic-sensitive ion channel Transient Receptor...
3.
Fu S, Thompson C, Ali A, Wang W, Chapple J, Mitchison H, et al.
Osteoarthritis Cartilage
. 2019 Mar;
27(7):1064-1074.
PMID: 30922983
Objective: Physiological mechanical loading reduces inflammatory signalling in numerous cell types including articular chondrocytes however the mechanism responsible remains unclear. This study investigates the role of chondrocyte primary cilia and...
4.
Xu J, Nyga A, Li W, Zhang X, Gavara N, Knight M, et al.
Eur Cell Mater
. 2018 Oct;
36:142-155.
PMID: 30280372
Many studies report the adverse responses to metal-on-metal (MoM) hip prostheses, with tissues surrounding failed MoM hip prostheses revealing abundant tissue necrosis and fibrosis. These local effects appear to be...
5.
Thompson C, Plant J, Wann A, Bishop C, Novak P, Mitchison H, et al.
Eur Cell Mater
. 2017 Sep;
34:128-141.
PMID: 28929469
Tissue engineering-based therapies targeting cartilage diseases, such as osteoarthritis, require in vitro expansion of articular chondrocytes. A major obstacle for these therapies is the dedifferentiation and loss of phenotype accompanying...
6.
Snodgrass C, AHearn M, Aceituno F, Afanasiev V, Bagnulo S, Bauer J, et al.
Philos Trans A Math Phys Eng Sci
. 2017 May;
375(2097).
PMID: 28554971
We present a summary of the campaign of remote observations that supported the European Space Agency's Rosetta mission. Telescopes across the globe (and in space) followed comet 67P/Churyumov-Gerasimenko from before...
7.
Delaine-Smith R, Burney S, Balkwill F, Knight M
J Mech Behav Biomed Mater
. 2016 Mar;
60:401-415.
PMID: 26974584
Mechanical characterisation of soft biological tissues using standard compression or tensile testing presents a significant challenge due to specimen geometrical irregularities, difficulties in cutting intact and appropriately sized test samples,...
8.
Sliogeryte K, Botto L, Lee D, Knight M
Osteoarthritis Cartilage
. 2015 Dec;
24(5):912-20.
PMID: 26706702
Objective: Chondrocyte dedifferentiation is known to influence cell mechanics leading to alterations in cell function. This study examined the influence of chondrocyte dedifferentiation in monolayer on cell viscoelastic properties and...
9.
Wang Z, Wann A, Thompson C, Hassen A, Wang W, Knight M
Osteoarthritis Cartilage
. 2015 Oct;
24(3):544-54.
PMID: 26493329
Objectives: Primary cilia are microtubule based organelles which control a variety of signalling pathways important in cartilage development, health and disease. This study examines the role of the intraflagellar transport...
10.
Wang Z, Irianto J, Kazun S, Wang W, Knight M
Osteoarthritis Cartilage
. 2014 Dec;
23(2):289-99.
PMID: 25450844
Objectives: Osteoarthritis (OA) is associated with a gradual reduction in the interstitial osmotic pressure within articular cartilage. The aim of this study was to compare the effects of sudden and...