M M Halldin
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Explore the profile of M M Halldin including associated specialties, affiliations and a list of published articles.
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28
Citations
137
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Recent Articles
1.
Segerdahl M, Rother M, Halldin M, Popescu T, Schaffler K
Eur J Pain
. 2024 Jun;
28(10):1656-1673.
PMID: 38864733
Background: The TRPV1 receptor is a key molecule in pain generation. Previous development of oral TRPV1-antagonists was halted due to systemic heat insensitivity and body temperature alterations. The present Phase...
2.
Onnestam K, Nilsson B, Rother M, Rein-Hedin E, Bylund J, Anderer P, et al.
J Prev Alzheimers Dis
. 2023 Oct;
10(4):778-789.
PMID: 37874100
Background: ACD856 is a positive allosteric modulator of tropomyosin receptor kinase (Trk) receptors which has shown to have pro-cognitive and anti-depressant-like effects in various animal models. It is currently in...
3.
Sjogren E, Kullenberg T, Jonzon B, Segerdahl M, Stalberg O, Halldin M, et al.
Eur J Pain
. 2018 Mar;
22(7):1214-1228.
PMID: 29504187
Background: The transient receptor potential cation channel subfamily V 1 (TRPV1) is involved in nociception and has thus been of interest for drug developers, as a target for novel analgesics....
4.
Sjogren E, Halldin M, Stalberg O, Sundgren-Andersson A
Eur J Pain
. 2018 Jan;
22(5):889-903.
PMID: 29377430
Background: The transient receptor potential vanilloid receptor 1 (TRPV1) is a nonselective cation channel involved in the mediation of peripheral pain to the central nervous system. As such, the TRPV1...
5.
Sohlberg E, Halldin M, Annas A, Konigsson K, Jansson B, Pehrson R, et al.
J Pharmacol Toxicol Methods
. 2012 Nov;
67(1):1-4.
PMID: 23138149
Introduction: Drugs are most commonly administered orally, but some potential drug candidates are not suited for oral administration due to poor absorption, high first pass metabolism or gastrointestinal side effects....
6.
Sohlenius-Sternbeck A, Chelpin H, Orzechowski A, Halldin M
Drug Metab Dispos
. 2000 May;
28(6):695-700.
PMID: 10820143
The metabolism of sameridine (LPB) (an amide-type local anesthetic-analgesic agent with a hexyl side chain) to carboxylic acid derivatives by isolated male rat hepatocytes was studied using gradient reversed-phase HPLC...
7.
Liquid chromatographic bioanalytical determination of ropivacaine, bupivacaine and major metabolites
Arvidsson T, Askemark Y, Halldin M
Biomed Chromatogr
. 1999 Jul;
13(4):286-92.
PMID: 10416062
Bioanalytical methods for the determination of ropivacaine, bupivacaine and their major metabolites in urine and blood plasma are presented. Ropivacaine is a new local anaesthetic drug mainly used for surgery...
8.
Danielsson B, Danielson M, Boo E, Arvidsson T, Halldin M
Pharmacol Toxicol
. 1997 Aug;
81(2):90-6.
PMID: 9298506
The relationship between free drug concentration and toxicity of bupivacaine and ropivacaine, a new local anaesthetic agent, was studied in a pregnant rat model. The compounds were given subcutaneously to...
9.
Szirmai M, Beck O, Stephansson N, Halldin M
J Anal Toxicol
. 1996 Nov;
20(7):573-8.
PMID: 8934309
The major urinary metabolite of delta 1-tetrahydrocannabinol (delta 1-THC) (1), delta 1-THC-7-oic acid (2), has been extensively studied for several purposes, including testing in the workplace for drug abuse. Immunoassays...
10.
Halldin M, Bredberg E, Angelin B, Arvidsson T, Askemark Y, Elofsson S, et al.
Drug Metab Dispos
. 1996 Sep;
24(9):962-8.
PMID: 8886605
The pharmacokinetics, biotransformation, and urinary excretion of ropivacaine (Naropin), a new local anesthetic agent, have been studied in six healthy male volunteers after a 15-min iv infusion of 152 mumol...