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M Lipsitch

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Recent Articles
1.
De Salazar P, Lu F, Hay J, Gomez-Barroso D, Fernandez-Navarro P, Martinez E, et al.
medRxiv . 2021 Feb; PMID: 33532788
Designing public health responses to outbreaks requires close monitoring of population-level health indicators in real-time. Thus, an accurate estimation of the epidemic curve is critical. We propose an approach to...
2.
De Salazar P, Gomez-Barroso D, Pampaka D, Gil J, Penalver B, Fernandez-Escobar C, et al.
Epidemiol Infect . 2020 Oct; 148:e268. PMID: 33081851
During the first months of the severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) epidemic in 2020, Spain implemented an initial lockdown period on 15 March followed by a strengthened lockdown period on...
3.
Goldstein E, Lipsitch M, Cevik M
medRxiv . 2020 Aug; PMID: 32743609
Background: There is limited information on the effect of age on the transmission of SARS-CoV-2 infection in different settings, including primary, secondary and high schools, households, and the whole community....
4.
De Salazar P, Niehus R, Taylor A, Buckee C, Lipsitch M
medRxiv . 2020 Jun; PMID: 32511458
Cases from the ongoing outbreak of atypical pneumonia caused by the 2019 novel coronavirus (2019-nCoV) exported from mainland China can lead to self-sustained outbreaks in other populations. Internationally imported cases...
5.
Lipsitch M, Goldstein E, Ray G, Fireman B
Epidemiol Infect . 2019 Nov; 147:e306. PMID: 31774051
Vaccine effectiveness studies are subject to biases due to depletion-of-persons at risk of infection, or at especially high risk of infection, at different rates from different groups (depletion-of-susceptibles bias), a...
6.
Mahmud A, Lipsitch M, Goldstein E
Epidemiol Infect . 2019 May; 147:e184. PMID: 31063110
There is limited information on the roles of different age groups in propagating pertussis outbreaks, and the temporal changes in those roles since the introduction of acellular pertussis vaccines. The...
7.
Abuelezam N, McCormick A, Surface E, Fussell T, Freedberg K, Lipsitch M, et al.
Epidemiol Infect . 2019 Mar; 147:e122. PMID: 30869008
UNAIDS established fast-track targets of 73% and 86% viral suppression among human immunodeficiency virus (HIV)-positive individuals by 2020 and 2030, respectively. The epidemiologic impact of achieving these goals is unknown....
8.
Georgieva M, Kagedan L, Lu Y, Thompson C, Lipsitch M
mBio . 2018 Mar; 9(2). PMID: 29535198
Genomic analysis reveals extensive sequence variation and hot spots of recombination in surface proteins of While this phenomenon is commonly attributed to diversifying selection by host immune responses, there is...
9.
Masala G, Lipsitch M, Bottomley C, Flasche S
J R Soc Interface . 2017 Nov; 14(136). PMID: 29093131
The competitive pressure from non-vaccine serotypes may have helped pneumococcal conjugate vaccines (PCVs) to limit vaccine-type (VT) serotype prevalence. We aimed to investigate if, consequently, the indirect protection of vaccines...
10.
Palmer M, Lipsitch M, Moxon E, Bayliss C
mBio . 2013 Jan; 4(1):e00430-12. PMID: 23300246
Unlabelled: Simple sequence repeat (SSR) tracts produce stochastic on-off switching, or phase variation, in the expression of a panoply of surface molecules in many bacterial commensals and pathogens. A change...