M L Funderburgh
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Explore the profile of M L Funderburgh including associated specialties, affiliations and a list of published articles.
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15
Citations
398
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Recent Articles
1.
Funderburgh J, Funderburgh M, Mann M, Corpuz L, Roth M
J Biol Chem
. 2001 Sep;
276(47):44173-8.
PMID: 11555658
Keratocytes of the corneal stroma secrete a unique population of proteoglycan molecules considered essential for corneal transparency. In healing corneal wounds, keratocytes exhibit a myofibroblastic phenotype in response to transforming...
2.
Tasheva E, Funderburgh J, Funderburgh M, Corpuz L, Conrad G
DNA Seq
. 1999 Nov;
10(1):67-74.
PMID: 10565548
Keratocan is one of the three major keratan sulfate proteoglycans characteristically expressed in cornea. We have isolated cDNA and genomic clones and determined the sequence of the entire human keratocan...
3.
Tasheva E, Funderburgh M, McReynolds J, Funderburgh J, Conrad G
J Biol Chem
. 1999 Jun;
274(26):18693-701.
PMID: 10373482
Mimecan is a proteoglycan expressed by many connective tissues. It was originally isolated in a truncated form as a bone-associated glycoprotein, osteoglycin, and was considered an osteoinductive factor. Recently, we...
4.
Funderburgh J, Hevelone N, Roth M, Funderburgh M, Rodrigues M, Nirankari V, et al.
Invest Ophthalmol Vis Sci
. 1998 Sep;
39(10):1957-64.
PMID: 9727420
Purpose: Corneas with scars and certain chronic pathologic conditions contain highly sulfated dermatan sulfate, but little is known of the core proteins that carry these atypical glycosaminoglycans. In this study...
5.
Funderburgh J, Corpuz L, Roth M, Funderburgh M, Tasheva E, Conrad G
J Biol Chem
. 1997 Nov;
272(44):28089-95.
PMID: 9346963
Bovine cornea contains three unique keratan sulfate proteoglycans (KSPGs), of which two (lumican and keratocan) have been characterized using molecular cloning. The gene for the third protein (KSPG25) has not...
6.
Funderburgh J, Mitschler R, Funderburgh M, Roth M, Chapes S, Conrad G
Invest Ophthalmol Vis Sci
. 1997 May;
38(6):1159-67.
PMID: 9152235
Purpose: Keratan sulfate proteoglycans (KSPGs) of the cornea exhibit a characteristic change in glycosylation resulting from stromal inflammation and scarring. To examine potential roles for these molecules in the pathobiology...
7.
Funderburgh J, Funderburgh M, Mann M, Prakash S, Conrad G
J Biol Chem
. 1996 Dec;
271(49):31431-6.
PMID: 8940154
Keratan sulfate proteoglycans (KSPGs) are the major proteoglycans of the cornea and are secreted by keratocytes in the corneal stroma. Previous studies have been able to show only transient secretion...
8.
Corpuz L, Funderburgh J, Funderburgh M, Bottomley G, Prakash S, Conrad G
J Biol Chem
. 1996 Apr;
271(16):9759-63.
PMID: 8621655
Previous studies showed that the keratan sulfate-containing proteoglycans of bovine corneal stroma contain three unique core proteins designated 37A, 37B, and 25 (Funderburgh, J. L., Funderburgh, M. L., Mann, M....
9.
Funderburgh J, Funderburgh M, Hevelone N, Stech M, Justice M, Liu C, et al.
Invest Ophthalmol Vis Sci
. 1995 Oct;
36(11):2296-303.
PMID: 7558724
Purpose: Lumican is a major proteoglycan of vertebrate cornea. This study characterizes mouse lumican, its molecular form, cDNA sequence, and chromosomal localization. Methods: Lumican sequence was determined from cDNA clones...
10.
Funderburgh J, Funderburgh M, Brown S, Vergnes J, Hassell J, Mann M, et al.
J Biol Chem
. 1993 Jun;
268(16):11874-80.
PMID: 8099356
Amino acid sequence from tryptic peptides of three different bovine corneal keratan sulfate proteoglycan (KSPG) core proteins (designated 37A, 37B, and 25) showed similarities to the sequence of a chicken...