M L Drumm
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Explore the profile of M L Drumm including associated specialties, affiliations and a list of published articles.
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41
Citations
1945
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Recent Articles
1.
Bonfield T, Hodges C, Cotton C, Drumm M
J Leukoc Biol
. 2012 Aug;
92(5):1111-22.
PMID: 22859830
The absence or reduction of CFTR function causes CF and results in a pulmonary milieu characterized by bacterial colonization and unresolved inflammation. The ineffectiveness at controlling infection by species such...
2.
Li W, Sun L, Corey M, Zou F, Lee S, Cojocaru A, et al.
Clin Genet
. 2010 Aug;
79(2):136-46.
PMID: 20681990
It is generally presumed that the cystic fibrosis (CF) population is relatively homogeneous, and predominantly of European origin. The complex ethnic make-up observed in the CF patients collected by the...
3.
Blackman S, Hsu S, Ritter S, Naughton K, Wright F, Drumm M, et al.
Diabetologia
. 2009 Jul;
52(9):1858-65.
PMID: 19585101
Aims/hypothesis: Insulin-requiring diabetes affects 25-50% of young adults with cystic fibrosis (CF). Although the cause of diabetes in CF is unknown, recent heritability studies in CF twins and siblings indicate...
4.
Hillian A, Londono D, Dunn J, Goddard K, Pace R, Knowles M, et al.
Genes Immun
. 2008 Jun;
9(6):501-8.
PMID: 18563170
Cystic fibrosis pulmonary disease is characterized by excessive and prolonged inflammation. CF Pulmonary disease severity exhibits considerable variation that, to some extent, appears to be due to the presence of...
5.
Drumm M
Curr Protoc Hum Genet
. 2008 Apr;
Chapter 5:Unit 5.4.
PMID: 18428292
Chromosome jumping allows the use of one point on a chromosome as a starting point for exploring another potentially distant point on the same chromosome without cloning the intervening sequences...
6.
Jin R, Hodges C, Drumm M, Palmert M
J Med Genet
. 2006 Jun;
43(6):e29.
PMID: 16740913
Background: Delayed puberty is common among individuals with cystic fibrosis (CF) and is usually attributed to chronic disease and/or poor nutrition. However, it has recently been recognised that pubertal delay...
7.
Drumm M
Respir Res
. 2001 Nov;
2(3):125-8.
PMID: 11686874
The availability of molecular tools to carry out genotyping has led to a flurry of association studies between specific genes and clinical indices of disease or disease susceptibility. Human studies,...
8.
Brady K, Kelley T, Drumm M
Am J Physiol Lung Cell Mol Physiol
. 2001 Oct;
281(5):L1173-9.
PMID: 11597909
Epithelia of humans and mice with cystic fibrosis are unable to secrete chloride in response to a chloride gradient or to cAMP-elevating agents. Bioelectrical properties measured using the nasal transepithelial...
9.
Steagall W, Drumm M
Gastroenterology
. 1999 May;
116(6):1379-88.
PMID: 10348821
Background & Aims: The cystic fibrosis transmembrane conductance regulator (CFTR) can be activated by pharmacological manipulation of the protein kinase A pathway in cell lines. Our goals were to stimulate...
10.
Chmiel J, Drumm M, Konstan M, Ferkol T, Kercsmar C
Pediatrics
. 1999 Apr;
103(4 Pt 1):823-6.
PMID: 10103316
In this report, we present an asymptomatic infant, seen for a second opinion, who was given the diagnosis of cystic fibrosis (CF) as a neonate based on the presence of...