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M Kawaichi

Explore the profile of M Kawaichi including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 38
Citations 1193
Followers 0
Related Specialties
Biochemistry
Cell Biology
Genetics
Top 10 Co-Authors
T Honjo
O HAYAISHI
K Ueda
Y Hamaguchi
C Oka
T Furukawa
N Matsunami
T Kokubo
Y Ishida
M Nishi
Published In
J Biol Chem
Proc Natl Acad Sci U S A
Genomics
Nucleic Acids Res
Princess Takamatsu Symp
Affiliations
Soon will be listed here.
Recent Articles
1.
Role of Deltex-1 as a transcriptional regulator downstream of the Notch receptor
Yamamoto N, Yamamoto S, Inagaki F, Kawaichi M, Fukamizu A, Kishi N, et al.
J Biol Chem . 2001 Sep; 276(48):45031-40. PMID: 11564735
Intercellular signaling through the cell-surface receptor Notch plays important roles in a variety of developmental processes as well as in pathogenesis of some human cancers and genetic disorders. However, the...
2.
Requirement for yeast TAF145 function in transcriptional activation of the RPS5 promoter that depends on both core promoter structure and upstream activating sequences
Tsukihashi Y, Kawaichi M, Kokubo T
J Biol Chem . 2001 May; 276(28):25715-26. PMID: 11337503
The general transcription factor TFIID has been shown to be involved in both core promoter recognition and the transcriptional activation of eukaryotic genes. We recently isolated TAF145 (one of TFIID...
3.
p48 subunit of mouse PTF1 binds to RBP-Jkappa/CBF-1, the intracellular mediator of Notch signalling, and is expressed in the neural tube of early stage embryos
Obata J, Yano M, Mimura H, Goto T, Nakayama R, Mibu Y, et al.
Genes Cells . 2001 Apr; 6(4):345-60. PMID: 11318877
Background: Development of the pancreas and the nervous tissues is regulated by common transcription factors. A basic helix-loop-helix protein, p48 of pancreas transcription factor 1 (PTF1), is essential for differentiation...
4.
Mutations in the TATA-binding protein, affecting transcriptional activation, show synthetic lethality with the TAF145 gene lacking the TAF N-terminal domain in Saccharomyces cerevisiae
Kobayashi A, Miyake T, Ohyama Y, Kawaichi M, Kokubo T
J Biol Chem . 2000 Oct; 276(1):395-405. PMID: 11035037
The general transcription factor TFIID, which is composed of the TATA box-binding protein (TBP) and a set of TBP-associated factors (TAFs), is crucial for both basal and regulated transcription by...
5.
A role of transcriptional activators as antirepressors for the autoinhibitory activity of TATA box binding of transcription factor IID
Kotani T, Banno K, Ikura M, Hinnebusch A, Nakatani Y, Kawaichi M, et al.
Proc Natl Acad Sci U S A . 2000 Jun; 97(13):7178-83. PMID: 10852950
The TATA box-binding activity of transcription factor IID (TFIID) is autoinhibited by the N-terminal domain of the Drosophila TATA box-binding protein- (TBP) associated factor 230/yeast TBP-associated factor 145 subunit, which...
6.
Impaired core promoter recognition caused by novel yeast TAF145 mutations can be restored by creating a canonical TATA element within the promoter region of the TUB2 gene
Tsukihashi Y, Miyake T, Kawaichi M, Kokubo T
Mol Cell Biol . 2000 Mar; 20(7):2385-99. PMID: 10713163
The general transcription factor TFIID, which is composed of TATA-binding protein (TBP) and an array of TBP-associated factors (TAFs), has been shown to play a crucial role in recognition of...
7.
Identification of highly conserved amino-terminal segments of dTAFII230 and yTAFII145 that are functionally interchangeable for inhibiting TBP-DNA interactions in vitro and in promoting yeast cell growth in vivo
Kotani T, Miyake T, Tsukihashi Y, Hinnebusch A, Nakatani Y, Kawaichi M, et al.
J Biol Chem . 1998 Nov; 273(48):32254-64. PMID: 9822704
TFIID is a multiprotein complex composed of TBP and several TAFIIs. Small amino-terminal segments (TAF N-terminal domain (TAND)) of Drosophila TAFII230 (dTAFII230) and yeast TAFII145 (yTAFII145) bind strongly to TBP...
8.
Disruption of the mouse RBP-J kappa gene results in early embryonic death
Oka C, Nakano T, Wakeham A, de la Pompa J, Mori C, Sakai T, et al.
Development . 1995 Oct; 121(10):3291-301. PMID: 7588063
The RBP-J kappa protein is a transcription factor that recognizes the sequence C(T)GTGGGGA. The RBP-J kappa gene is highly conserved in a wide variety of species and the Drosophila homologue...
9.
Constitutive activation of mitogen-activated protein (MAP) kinases in human renal cell carcinoma
Oka H, Chatani Y, Hoshino R, Ogawa O, Kakehi Y, Terachi T, et al.
Cancer Res . 1995 Sep; 55(18):4182-7. PMID: 7664295
Mitogen-activated protein kinases (MAPKs) play a pivotal role in the mitogenic signal transduction pathway and are essential components of the MAPK cascade, which includes MEK (also known as MAP kinase...
10.
Loss of immunostaining of the RBP-J kappa transcription factor upon F9 cell differentiation induced by retinoic acid
Sakai T, Furukawa T, Iwanari H, Oka C, Nakano T, Kawaichi M, et al.
J Biochem . 1995 Sep; 118(3):621-8. PMID: 8690727
RBP-Jkappa is a novel type of transcriptional regulatory protein that does not contain any known DNA-binding motif. We raised anti-RBP-Jkappa monoclonal antibodies (K0043 and T6709) to investigate the roles of...