M J van Steenbergen
Overview
Explore the profile of M J van Steenbergen including associated specialties, affiliations and a list of published articles.
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Articles
26
Citations
249
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Recent Articles
11.
den Brok M, Nuijen B, Kettenes-van den Bosch J, van Steenbergen M, Buluran J, Harvey M, et al.
PDA J Pharm Sci Technol
. 2005 Dec;
59(5):285-97.
PMID: 16316064
C1311 (5-[[2-(diethylamino)ethyl]amino]-8-hydroxyimidazo [4,5,1-de]-acridin-6-one-dihydrochloride trihydrate) is the lead compound from the group of imidazoacridinones, a novel group of rationally designed anticancer agents. C1311 shows significant cytotoxic activity in vitro and in...
12.
Janssen A, Talsma H, van Steenbergen M, de Jong K
Langmuir
. 2005 Mar;
20(1):41-5.
PMID: 15744997
In this paper, we show that water inside mesoporous cavities in zeolites can be supercooled to ca. -40 degrees C at which point homogeneous nucleation of the water takes place....
13.
Bouma M, Nuijen B, Harms R, Rice J, Nowotnik D, Stewart D, et al.
Drug Dev Ind Pharm
. 2003 Nov;
29(9):981-95.
PMID: 14606662
AP 5280 is a novel polymer-conjugated platinum anticancer agent showing promising in vitro and in vivo activity against solid tumors. The aim of this study was to develop a parenteral...
14.
Bouma M, Nuijen B, Sava G, Perbellini A, Flaibani A, van Steenbergen M, et al.
Int J Pharm
. 2002 Nov;
248(1-2):247-59.
PMID: 12429478
This paper describes the development of a stable pharmaceutical dosage form for NAMI-A, a novel antimetastatic ruthenium complex, for Phase I testing. NAMI-A drug substance was characterized using several spectrometric...
15.
Nijsen J, van het Schip A, van Steenbergen M, Zielhuis S, Kroon-Batenburg L, van de Weert M, et al.
Biomaterials
. 2002 Apr;
23(8):1831-9.
PMID: 11950053
Holmium-loaded microspheres are useful systems in radio-embolization therapy of liver metastases. For administration to a patient, the holmium-loaded microspheres have to be irradiated in a nuclear reactor to become radioactive....
16.
Cadee J, van Steenbergen M, Versluis C, Heck A, Underberg W, Den Otter W, et al.
Pharm Res
. 2001 Nov;
18(10):1461-7.
PMID: 11697473
Purpose: The oxidation of recombinant human interleukin-2 (rhlL-2) by potassium peroxodisulfate (KPS) with or without N,N,N',N'-tetramethylethylenediamine (TEMED), which are used for the preparation of dextran-based hydrogels, was investigated. Methods: The...
17.
Nijsen J, van Steenbergen M, Kooijman H, Talsma H, van de Weert M, van Rijk P, et al.
Biomaterials
. 2001 Sep;
22(22):3073-81.
PMID: 11575483
Holmium-loaded PLLA microspheres are useful systems in radioembolization therapy of liver metastases because of their low density, biodegradability and favourable radiation characteristics. Neutron activated Ho-loaded microspheres showed a surprisingly low...
18.
Steendam R, van Steenbergen M, Hennink W, Frijlink H, Lerk C
J Control Release
. 2001 Feb;
70(1-2):71-82.
PMID: 11166409
Different molecular weight grades of poly(DL-lactic acid) were applied as release controlling excipients in tablets for oral drug administration. The role of molecular weight and glass transition in the mechanism...
19.
van de Wetering P, van Steenbergen M, Crommelin D, Hennink W
J Control Release
. 2000 Jan;
64(1-3):193-203.
PMID: 10640657
Random copolymers of 2-(dimethylamino)ethyl methacrylate (DMAEMA) with ethoxytriethylene glycol methacrylate (triEGMA) or N-vinylpyrrolidone (NVP) of different molecular weights and compositions were synthesized, characterized and evaluated as polymeric transfectants in vitro....
20.
van de Wetering P, Moret E, van Steenbergen M, Hennink W
Bioconjug Chem
. 1999 Jul;
10(4):589-97.
PMID: 10411456
A number of water-soluble cationic carriers was evaluated as transfectant. Almost all studied cationic methacrylate/methacrylamide polymers were able to condense the structure of plasmid DNA, yielding polymer/plasmid complexes (polyplexes) with...