M J van den Hoven
Overview
Explore the profile of M J van den Hoven including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
222
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Recent Articles
1.
van den Hoven M, Wijnhoven T, Li J, Zcharia E, Dijkman H, Wismans R, et al.
Kidney Int
. 2007 Nov;
73(3):278-87.
PMID: 18046314
Heparan sulfate in the glomerular basement membrane has been considered crucial for charge-selective filtration. In many proteinuric diseases, increased glomerular expression of heparanase is associated with decreased heparan sulfate. Here,...
2.
Rops A, van den Hoven M, Baselmans M, Lensen J, Wijnhoven T, van den Heuvel L, et al.
Kidney Int
. 2007 Oct;
73(1):52-62.
PMID: 17914352
Heparan sulfate (HS) proteoglycans by playing key roles in the leukocyte-endothelial interactions are thought to mediate inflammatory cell influx in proliferative glomerulonephritis. Here, we evaluated the specific features within glomerular...
3.
Rops A, Gotte M, Baselmans M, van den Hoven M, Steenbergen E, Lensen J, et al.
Kidney Int
. 2007 Sep;
72(10):1204-15.
PMID: 17805240
During the heterologous phase of experimental anti-glomerular basement membrane (anti-GBM) nephritis, leukocyte influx peaks within hours, whereas albuminuria occurs within 1 day. In the subsequent autologous phase, endogenous anti-GBM IgG...
4.
van den Hoven M, Rops A, Vlodavsky I, Levidiotis V, Berden J, van der Vlag J
Kidney Int
. 2007 May;
72(5):543-8.
PMID: 17519955
Heparanase is an endo-beta(1-4)-D-glucuronidase that degrades heparan sulfate (HS) polysaccharide side chains. The role of heparanase in metastasis, angiogenesis, and inflammation has been established. Recent data suggest a role for...
5.
van den Hoven M, Rops A, Bakker M, Aten J, Rutjes N, Roestenberg P, et al.
Kidney Int
. 2006 Oct;
70(12):2100-8.
PMID: 17051139
In overt diabetic nephropathy (DNP), an increase in the permeability of the glomerular basement membrane (GBM) has been associated with a loss of negatively charged heparan sulfates (HS) in the...
6.