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J van der Vlag

Explore the profile of J van der Vlag including associated specialties, affiliations and a list of published articles. Areas
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Articles 41
Citations 1238
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Recent Articles
1.
Kouwenberg M, Pulskens W, Diepeveen L, Bakker-van Bebber M, Dinarello C, Netea M, et al.
PLoS One . 2021 May; 16(5):e0251809. PMID: 34029331
The dendritic cell (DC)-derived cytokine profile contributes to naive T cell differentiation, thereby directing the immune response. IL-37 is a cytokine with anti-inflammatory characteristics that has been demonstrated to induce...
2.
Kouwenberg M, Rops A, Bakker-van Bebber M, Diepeveen L, Gotte M, Hilbrands L, et al.
PLoS One . 2020 Jul; 15(7):e0230835. PMID: 32701966
Syndecan-1 (Sdc-1) is a heparan sulfate proteoglycan that can bind cytokines and chemokines via its heparan sulfate side chains, and has immunomodulatory properties in experimental models. Sdc-1 expression has been...
3.
van Gemst J, Kouwenberg M, Rops A, van Kuppevelt T, Berden J, Rabelink T, et al.
PLoS One . 2018 Sep; 13(9):e0201560. PMID: 30248108
Introduction: Proliferative glomerulonephritis manifests in a range of renal diseases and is characterized by the influx of inflammatory cells into the glomerulus. Heparan sulfate (HS) is an important (co-)receptor for...
4.
Uijtdewilligen P, Versteeg E, van de Westerlo E, van der Vlag J, Daamen W, van Kuppevelt T
Biomed Res Int . 2018 Sep; 2018:9873471. PMID: 30228991
Glycosaminoglycans are important for cell signaling and therefore for proper embryonic development and adult homeostasis. Expressions of genes involved in proteoglycan/glycosaminoglycan (GAG) metabolism and of genes coding for growth factors...
5.
van de Vrie M, Deegens J, Eikmans M, van der Vlag J, Hilbrands L
Am J Transplant . 2016 Oct; 17(5):1160-1166. PMID: 27743494
Urine represents a noninvasive source in which proteins and nucleic acids can be assessed. Such analytes may function as biomarkers to monitor kidney graft pathology at every desired frequency, thereby...
6.
Kouwenberg M, Jacobs C, van der Vlag J, Hilbrands L
PLoS One . 2016 Aug; 11(8):e0159986. PMID: 27525971
Introduction: Tolerogenic dendritic cells (DCs) have the potential to prolong graft survival after transplantation. Tolerogenic DCs are in general characterized by a low expression of co-stimulatory molecule and a high...
7.
Pieterse E, Hofstra J, Berden J, Herrmann M, Dieker J, van der Vlag J
Clin Exp Immunol . 2014 Apr; 179(1):68-74. PMID: 24758196
In addition to disturbed apoptosis and insufficient clearance of apoptotic cells, there is recent evidence for a role of neutrophils in the aetiopathogenesis of systemic lupus erythematosus (SLE). In response...
8.
de Vries M, Ramos L, Lacroix R, DHauwers K, Hendriks J, Kremer J, et al.
Andrology . 2013 Mar; 1(3):421-30. PMID: 23536489
During the last phase of spermatogenesis, called spermiogenesis, the nucleosome-based chromatin structure is replaced by a protamine-based DNA packaging. Not much is known about the chromatin remodelling involved in humans...
9.
Fransen J, Dieker J, Hilbrands L, Berden J, van der Vlag J
Apoptosis . 2010 Oct; 16(1):86-93. PMID: 20972831
In our research on the role of apoptosis in the pathogenesis of the autoimmune disease systemic lupus erythematosus (SLE), we aim to evaluate the effects of early and late apoptotic...
10.
DE Mateo S, Ramos L, van der Vlag J, de Boer P, Oliva R
Int J Androl . 2010 Jun; 34(3):256-67. PMID: 20569271
A two-step gradient density centrifugation system has been set up to isolate two contrasting sperm populations of normozoospermic and oligoasthenoteratozoospermic (OAT) men. High- and low-density fractions were characterized by total...