M J McPhaul
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Explore the profile of M J McPhaul including associated specialties, affiliations and a list of published articles.
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85
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1140
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Recent Articles
1.
Lephart E, Herbst M, McPhaul M
Endocrine
. 2010 Dec;
3(1):25-31.
PMID: 21153233
The conversion of androgens to estrogens is catalyzed by the aromatase cytochrome P-450 (P-450(AROM)) in a veriety of tissues and cell types in vertebrates. The manner in which aromatase activity...
2.
Avila D, Allman D, Gallo J, McPhaul M
Exp Biol Med (Maywood)
. 2003 Sep;
228(8):982-90.
PMID: 12968071
The pathogenesis of X-linked spinal and bulbar muscular atrophy (SBMA) has been traced to an expansion of repeated glutamine (Gln) residues within the amino terminus of the human androgen receptor...
3.
McPhaul M
J Investig Dermatol Symp Proc
. 2003 Aug;
8(1):1-5.
PMID: 12894986
Androgens mediate a wide range of processes during embryogenesis and in the adult. In mammals, although a number of steroids can be shown to exert androgenic effects using in vitro...
4.
Catalano S, Avila D, Marsico S, Wilson J, Glickman S, McPhaul M
Mol Cell Endocrinol
. 2002 Sep;
194(1-2):85-94.
PMID: 12242031
The external genitalia of the female spotted hyena are male in character, consistent with virilization by androgens during embryogenesis that results in the fusion of the vaginal labia to form...
5.
Zoppi S, Allman D, Gerard R, McPhaul M
J Mol Endocrinol
. 2001 Nov;
27(3):321-8.
PMID: 11719284
The androgen receptor (AR) and closely related members of the steroid receptor family have proven difficult to obtain in native form in large quantities. In the case of the human...
6.
Andriani F, Nan B, Yu J, Li X, Weigel N, McPhaul M, et al.
J Natl Cancer Inst
. 2001 Sep;
93(17):1314-24.
PMID: 11535706
Background: Adenovirus-mediated overexpression of the apoptosis-inducing protein Bax can induce apoptosis in prostate cancer cell lines. Constitutive overexpression of Bax could result in unwanted apoptosis in every site of accidental...
7.
McPhaul M, Young M
J Am Acad Dermatol
. 2001 Aug;
45(3 Suppl):S87-94.
PMID: 11511858
Androgens mediate a wide range of processes during embryogenesis and in the adult. In mammals, the principal androgens are testosterone and its 5alpha-reduced metabolite, 5alpha-dihydrotestosterone (DHT). Although these androgenic hormones...
8.
Avila D, Zoppi S, McPhaul M
J Steroid Biochem Mol Biol
. 2001 Jun;
76(1-5):135-42.
PMID: 11384871
The actions of androgens, principally testosterone and 5alpha-dihydrotestosterone, are mediated by a specific receptor protein, the androgen receptor (AR), which is encoded by a single-copy gene located on the human...
9.
Reutens A, Fu M, Wang C, Albanese C, McPhaul M, Sun Z, et al.
Mol Endocrinol
. 2001 May;
15(5):797-811.
PMID: 11328859
The androgen receptor (AR) is a ligand-regulated member of the nuclear receptor superfamily. The cyclin D1 gene product, which encodes the regulatory subunit of holoenzymes that phosphorylate the retinoblastoma protein...
10.
Lanzino M, Catalano S, Genissel C, Ando S, Carreau S, Hamra K, et al.
Biol Reprod
. 2001 Apr;
64(5):1439-43.
PMID: 11319149
It has long been recognized that individual cell types within the testes possess the capacity to synthesize estrogen. A number of studies on different species have demonstrated that the levels...