M J LaBonte
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Explore the profile of M J LaBonte including associated specialties, affiliations and a list of published articles.
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11
Citations
277
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Recent Articles
1.
Bohanes P, Yang D, Loupakis F, LaBonte M, Gerger A, Ning Y, et al.
Pharmacogenomics J
. 2014 Dec;
15(3):226-34.
PMID: 25487679
Integrins (ITGs) are key elements in cancer biology, regulating tumor growth, angiogenesis and lymphangiogenesis through interactions of the tumor cells with the microenvironment. Moving from the hypothesis that ITGs could...
2.
Benhaim L, Zhang W, Wakatsuki T, Yang D, Gerger A, Bohanes P, et al.
Pharmacogenomics J
. 2014 Oct;
15(3):235-40.
PMID: 25287073
In patients with breast cancer (BC), deregulation of estrogen receptor (ERα) activity may account for most resistance to endocrine therapies. Our previous study used a whole-human kinome siRNA screen to...
3.
Paez D, Gerger A, Zhang W, Yang D, LaBonte M, Benhanim L, et al.
Pharmacogenomics J
. 2013 Jul;
14(2):142-50.
PMID: 23817222
Wnt/β-catenin signaling has a central role in the development and progression of most colon cancers (CCs). Germline variants in Wnt/β-catenin pathway genes may result in altered gene function and/or activity,...
4.
Benhaim L, Gerger A, Bohanes P, Paez D, Wakatsuki T, Yang D, et al.
Pharmacogenomics J
. 2013 Jun;
14(2):135-41.
PMID: 23752739
This study was designed to analyze the gender-related association between SCN1A polymorphisms (voltage-gated sodium channels; α-subunit) and time-to-recurrence (TTR) in patients with colorectal cancer (CRC) treated with 5-fluoruracil (5-FU)-based adjuvant...
5.
Absenger G, Benhaim L, Szkandera J, Zhang W, Yang D, LaBonte M, et al.
Pharmacogenomics J
. 2013 Apr;
14(2):130-4.
PMID: 23567490
Recent evidence indicates a potential prognostic and predictive value for germline polymorphisms in genes involved in cell cycle control. We investigated the effect of cyclin D1 (CCND1) rs9344 G>A in...
6.
Benhaim L, Loupakis F, LaBonte M, Lenz H
J Hepatobiliary Pancreat Sci
. 2012 Jun;
19(5):528-35.
PMID: 22735932
For physicians facing patients with organ-limited metastases from colorectal cancer, tumor shrinkage and sterilization of micrometastatic disease is the main goal, giving the opportunity for secondary surgical resection. At the...
7.
Lee Y, Choi I, Ning Y, Kim N, Khatchadourian V, Yang D, et al.
Br J Cancer
. 2012 May;
106(11):1833-41.
PMID: 22617157
Background: Colorectal cancer (CRC) is a leading cause of death in the United States. Increased level of interleukin-8 (IL-8) and CXCR2 on tumours and in the tumour microenvironment has been...
8.
LaBonte M, Wilson P, Yang D, Zhang W, Ladner R, Ning Y, et al.
Ann Oncol
. 2011 Oct;
23(6):1455-64.
PMID: 21989330
Background: Lapatinib plus capecitabine emerged as an efficacious therapy in metastatic breast cancer (mBC). We aimed to identify germline single-nucleotide polymorphisms (SNPs) in genes involved in capecitabine catabolism and human...
9.
10.
Zhang W, Winder T, Ning Y, Pohl A, Yang D, Kahn M, et al.
Ann Oncol
. 2010 Jul;
22(1):104-109.
PMID: 20603437
Purpose: recent studies have found that KRAS mutations predict resistance to monoclonal antibodies targeting the epidermal growth factor receptor in metastatic colorectal cancer (mCRC). A polymorphism in a let-7 microRNA...