M J Berridge
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Explore the profile of M J Berridge including associated specialties, affiliations and a list of published articles.
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190
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Recent Articles
1.
Berridge M
Biochem Soc Trans
. 2006 Mar;
34(Pt 2):228-31.
PMID: 16545082
In cardiac cells, Ca2+ signals appear as brief transients responsible for controlling both contraction and transcription. Information may be encoded in these digital signals through changes in both frequency and...
2.
Berridge M
Biochem Soc Trans
. 2003 Sep;
31(Pt 5):930-3.
PMID: 14505451
Calcium regulates three different aspects of cardiac contraction. It drives pacemaker activity, excitation-contraction coupling and the transcriptional events that remodel the Ca(2+) signalling system in both health and disease.
3.
Tovey S, de Smet P, Lipp P, Thomas D, Young K, Missiaen L, et al.
J Cell Sci
. 2001 Dec;
114(Pt 22):3979-89.
PMID: 11739630
Elementary Ca(2+) signals, such as "Ca(2+) puffs", which arise from the activation of inositol 1,4,5-trisphosphate receptors, are building blocks for local and global Ca(2+) signalling. We characterized Ca(2+) puffs in...
4.
Berridge M
Novartis Found Symp
. 2001 Sep;
239:52-64; discussion 64-7, 150-9.
PMID: 11529316
Ca2+ is a universal second messenger used to regulate a wide range of cellular processes such as fertilization, proliferation, contraction, secretion, learning and memory. Cells derive signal Ca2+ from both...
5.
Bootman M, Lipp P, Berridge M
J Cell Sci
. 2001 Aug;
114(Pt 12):2213-22.
PMID: 11493661
Calcium (Ca(2+)) is a ubiquitous intracellular messenger, controlling a diverse range of cellular processes, such as gene transcription, muscle contraction and cell proliferation. The ability of a simple ion such...
6.
Berridge M, Lipp P, Bootman M
Nat Rev Mol Cell Biol
. 2001 Jun;
1(1):11-21.
PMID: 11413485
The universality of calcium as an intracellular messenger depends on its enormous versatility. Cells have a calcium signalling toolkit with many components that can be mixed and matched to create...
7.
Collins T, Lipp P, Berridge M, Bootman M
J Biol Chem
. 2001 May;
276(28):26411-20.
PMID: 11333261
Using confocal imaging of Rhod-2-loaded HeLa cells, we examined the ability of mitochondria to sequester Ca(2+) signals arising from different sources. Mitochondrial Ca(2+) (Ca(2+)mit) uptake was stimulated by inositol 1,4,5-trisphosphate...
8.
Bootman M, Collins T, Peppiatt C, Prothero L, Mackenzie L, de Smet P, et al.
Semin Cell Dev Biol
. 2001 Feb;
12(1):3-10.
PMID: 11162741
Calcium (Ca2+) is an almost universal intracellular messenger, controlling a diverse range of cellular processes, such as gene transcription, muscle contraction and cell proliferation. The ability of a simple ion...
9.
Mackenzie L, Bootman M, Berridge M, Lipp P
J Physiol
. 2001 Feb;
530(Pt 3):417-29.
PMID: 11158273
Excitation-contraction coupling (E-C coupling) was studied in isolated fluo-3-loaded rat atrial myocytes at 22 and 37 degrees C using rapid confocal microscopy. Within a few milliseconds of electrical excitation, spatially...
10.
Thomas D, Tovey S, Collins T, Bootman M, Berridge M, Lipp P
Cell Calcium
. 2000 Oct;
28(4):213-23.
PMID: 11032777
Quantifying the magnitude of Ca2+ signals from changes in the emission of fluorescent indicators relies on assumptions about the indicator behaviour in situ. Factors such as osmolarity, pH, ionic strength...