M Halbrugge
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Explore the profile of M Halbrugge including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
317
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Recent Articles
1.
Schneider-Schaulies J, Schneider-Schaulies S, Brinkmann R, Tas P, Halbrugge M, Walter U, et al.
Virology
. 1992 Dec;
191(2):765-72.
PMID: 1360181
Human immunodeficiency virus (HIV-1) infection in the human brain leads to characteristic neuropathological changes, which may result indirectly from interactions of the envelope glycoprotein gp120 with neurons and/or glial cells....
2.
Reinhard M, Halbrugge M, Scheer U, Wiegand C, Jockusch B, Walter U
EMBO J
. 1992 Jun;
11(6):2063-70.
PMID: 1318192
Vasoactive agents which elevate either cGMP or cAMP inhibit platelet activation by pathways sharing at least one component, the 46/50 kDa vasodilator-stimulated phosphoprotein (VASP). VASP is stoichiometrically phosphorylated by both...
3.
Eigenthaler M, Nolte C, Halbrugge M, Walter U
Eur J Biochem
. 1992 Apr;
205(2):471-81.
PMID: 1315268
Vasodilators capable of elevating cAMP or cGMP inhibit the activation of human platelets and stimulate the phosphorylation of a 46-kDa protein (vasodilator-stimulated phosphoprotein, VASP) mediated by cAMP-dependent protein kinase (PKA)...
4.
Halbrugge M, Eigenthaler M, Polke C, Walter U
Cell Signal
. 1992 Mar;
4(2):189-99.
PMID: 1319722
A specific 46,000/50,000 molecular weight protein substrate for both cAMP-dependent protein kinase (cAK) and cGMP-dependent protein kinase (cGK) extensively characterized and purified from human platelets was found to be present...
5.
Sandberg M, Butt E, Nolte C, Fischer L, Halbrugge M, Beltman J, et al.
Biochem J
. 1991 Oct;
279 ( Pt 2):521-7.
PMID: 1659381
A newly designed cyclic AMP (cAMP) analogue, Sp-5,6-dichloro-1-beta-D- ribofuranosylbenzimidazole-3',5'-monophosphorothioate (Sp-5,6-DCl-cBiMPS), and 8-(p-chlorophenylthio)-cAMP (8-pCPT-cAMP) were compared with respect to their chemical and biological properties in order to assess their potential as...
6.
Walter U, Halbrugge M, Nolte C, Eigenthaler M, Lohman S
Verh Dtsch Ges Inn Med
. 1991 Jan;
97:582-8.
PMID: 1808949
No abstract available.
7.
Halbrugge M, Walter U
J Chromatogr
. 1990 Nov;
521(2):335-43.
PMID: 2286641
Recently, the development of a monospecific antiserum against a 46,000/50,000-dalton membrane protein from human platelets which was stoichiometrically and reversibly phosphorylated in intact human platelets in response to vasodilators was...
8.
Halbrugge M, Friedrich C, Eigenthaler M, Schanzenbacher P, Walter U
J Biol Chem
. 1990 Feb;
265(6):3088-93.
PMID: 2154470
Recently, we reported the purification of a 46-kDa membrane-associated platelet protein which is phosphorylated in intact platelets and platelet membranes by cGMP- and cAMP-dependent protein kinases (Halbrügge, M., and Walter,...
9.
Halbrugge M, Walter U
Eur J Biochem
. 1989 Oct;
185(1):41-50.
PMID: 2806262
Cyclic-nucleotide-elevating vasodilators such as prostaglandin E1, prostacyclin, sodium nitroprusside and endothelium-derived relaxing factor inhibit both contraction of vascular smooth muscle cells and the aggregation of platelets at an early step...