M H Poutanen
Overview
Explore the profile of M H Poutanen including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
12
Citations
130
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Qin Y, Poutanen M, Novikov D
J Lipid Res
. 2000 Jan;
41(1):93-8.
PMID: 10627506
In addition to several other enzymes, the short-chain alcohol dehydrogenase superfamily includes a group of peroxisomal multifunctional enzymes involved in fatty acid and cholesterol side-chain beta-oxidation. Mammalian peroxisomal multifunctional enzyme...
2.
Puranen T, Kurkela R, Lakkakorpi J, Poutanen M, Itaranta P, Melis J, et al.
Endocrinology
. 1999 Jun;
140(7):3334-41.
PMID: 10385431
Human 17beta-hydroxysteroid dehydrogenase (17HSD) type 2 is a widely distributed enzyme that primarily converts the highly active 17beta-hydroxysteroids to their inactive keto forms. In the present study, full-length human 17HSD...
3.
Mustonen M, Isomaa V, Vaskivuo T, Tapanainen J, Poutanen M, Stenback F, et al.
J Clin Endocrinol Metab
. 1998 Apr;
83(4):1319-24.
PMID: 9543162
According to the current hypothesis, 17beta-hydroxysteroid dehydrogenases (17HSDs) regulate the extent of estrogen influence in the endometrium by converting estradiol (E2) locally into a biologically less active sex steroid, estrone...
4.
Mustonen M, Poutanen M, Kellokumpu S, de Launoit Y, Isomaa V, Vihko R, et al.
J Mol Endocrinol
. 1998 Mar;
20(1):67-74.
PMID: 9513083
17 beta-Hydroxysteroid dehydrogenase (17HSD) type 2 efficiently catalyzes the conversion of the high activity 17 beta-hydroxy forms of sex steroids into less potent 17-ketosteroids. In the present study in situ...
5.
Mustonen M, Poutanen M, Isomaa V, Vihko P, Vihko R
Biochem J
. 1997 Jul;
325 ( Pt 1):199-205.
PMID: 9224647
17beta-Hydroxysteroid dehydrogenases (17HSDs) are responsible for the conversion of low-activity sex steroids to more potent forms, and vice versa. 17HSD activity is essential for the biosynthesis of sex steroids in...
6.
Qin Y, Poutanen M, Helander H, Kvist A, Siivari K, Schmitz W, et al.
Biochem J
. 1997 Jan;
321 ( Pt 1):21-8.
PMID: 9003397
In the present study we have cloned and characterized a novel rat peroxisomal multifunctional enzyme (MFE) named perMFE-II. The purified 2-enoyl-CoA hydratase 2 with an M(r) of 31500 from rat...
7.
Miettinen M, Poutanen M, Vihko R
Int J Cancer
. 1996 Nov;
68(5):600-4.
PMID: 8938141
17beta-hydroxysteroid dehydrogenase (17HSD) type I converts the weakly active estrogen, estrone, into highly active estradiol. In addition to being essential for gonadal estradiol biosynthesis, the enzyme is also expressed in...
8.
Miettinen M, Mustonen M, Poutanen M, Isomaa V, Vihko R
Biochem J
. 1996 Mar;
314 ( Pt 3):839-45.
PMID: 8615778
17 beta-Hydroxysteroid dehydrogenase (17HSD) isoenzymes catalyse the interconversion between highly active 17 beta-hydroxy- and low-activity 17-keto-steroids and thereby regulate the biological activity of sex steroids. The present study was carried...
9.
Puranen T, Poutanen M, Peltoketo H, Vihko P, Vihko R
Biochem J
. 1994 Nov;
304 ( Pt 1):289-93.
PMID: 7998947
Several amino acid residues (Cys54, Tyr155, His210, His213 and His221) at a putative catalytic site of human 17 beta-hydroxysteroid dehydrogenase type 1 were mutated to Ala. Replacement of His221 by...
10.
Ghersevich S, Poutanen M, Martikainen H, Vihko R
J Endocrinol
. 1994 Oct;
143(1):139-50.
PMID: 7525828
The aim of this study was to examine the expression and regulation of type 1 17 beta-hydroxysteroid dehydrogenase (type 1 17-HSD) enzyme protein and mRNA, and 17-HSD activity in human...