M Goodhardt
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Explore the profile of M Goodhardt including associated specialties, affiliations and a list of published articles.
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Articles
23
Citations
167
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Recent Articles
1.
Brugat T, Gault N, Baccelli I, Maes J, Roborel de Climens A, Nguyen-Khac F, et al.
Leukemia
. 2009 Oct;
24(1):246-51.
PMID: 19847201
No abstract available.
2.
Abecassis I, Maes J, Carrier J, Hillion J, Goodhardt M, Medjber K, et al.
Leukemia
. 2007 Dec;
22(3):511-20.
PMID: 18094716
In the acute promyelocytic leukemia cell line, NB4, activation of the CD44 receptor triggers apoptosis. This pathway does not operate in the retinoid-maturation-resistant NB4-LR1 subclone. In this work, we show...
3.
Maes J, ONeill L, Cavelier P, Turner B, Rougeon F, Goodhardt M
J Immunol
. 2001 Jul;
167(2):866-74.
PMID: 11441093
Rearrangement of Ig H and L chain genes is highly regulated and takes place sequentially during B cell development. Several lines of evidence indicate that chromatin may modulate accessibility of...
4.
Maes J, Caspi Y, Rougeon F, Haimovich J, Goodhardt M
J Immunol
. 2000 Jul;
165(2):703-9.
PMID: 10878342
It has recently become clear that recombination of Ig genes is not restricted to B cell precursors but that secondary rearrangements can also occur under certain conditions in phenotypically immature...
5.
Coquilleau I, Cavelier P, Rougeon F, Goodhardt M
J Immunol
. 2000 Jan;
164(2):795-804.
PMID: 10623825
The intronic Ig kappa-light chain enhancer (Eikappa) has been implicated in regulation of transcription and Vkappa-Jkappa recombination at the kappa locus. To identify sequences within the Eikappa enhancer which are...
6.
Badie C, Goodhardt M, Waugh A, DOYEN N, Foray N, Calsou P, et al.
Cancer Res
. 1997 Oct;
57(20):4600-7.
PMID: 9377575
The 180BR cell line was derived from an acute lymphoblastic leukemia patient who overresponded to radiation therapy and died following radiation morbidity. 180BR cells are hypersensitive to the lethal effects...
7.
Cavelier P, Nato F, Coquilleau I, Rolink A, Rougeon F, Goodhardt M
Eur J Immunol
. 1997 Jul;
27(7):1626-31.
PMID: 9247570
To study the control of immunoglobulin kappa light chain gene rearrangement, we generated transgenic mice carrying a germ-line human kappa minilocus (HK) containing the J kappa-proximal V gene, V kappa...
8.
Mazur S, Goodhardt M, Feunteun J, de La Roche Saint Andre C
J Virol
. 1994 Sep;
68(9):5629-37.
PMID: 8057443
Hamster polyomavirus (HaPV) causes lymphomas when injected into newborn hamsters. These tumors are virus-free but accumulate large amounts of deleted extrachromosomal viral genomes. In order to identify the major sites...
9.
Kallenbach S, Babinet C, Pournin S, Cavelier P, Goodhardt M, Rougeon F
Eur J Immunol
. 1993 Aug;
23(8):1917-21.
PMID: 8344354
It is not known which cis-acting elements regulate kappa gene rearrangement. However, the onset of rearrangement coincides with the onset of transcription suggesting that common regulatory elements are used. We...
10.
Goodhardt M, Cavelier P, DOYEN N, Kallenbach S, Babinet C, Rougeon F
Eur J Immunol
. 1993 Aug;
23(8):1789-95.
PMID: 8344341
We have previously shown that unlike endogenous chi genes, unrearranged chi transgenes undergo V chi-J chi recombination in Tas well as B cells of transgenic mice. To determine whether the...