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M Frolich

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Articles 225
Citations 1687
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Recent Articles
1.
van Exel E, Eikelenboom P, Comijs H, Kurniawan C, Frolich M, Smit J, et al.
Tijdschr Psychiatr . 2011 Sep; 53(9):637-43. PMID: 21898320
Background: It has still not been established unequivocally whether vascular risk factors and inflammatory reactions, determined by heredity, are a cause or a result of Alzheimer's disease Aim: If the...
2.
Aziz N, Pijl H, Frolich M, Roelfsema F, Roos R
J Neuroendocrinol . 2011 Apr; 23(6):519-24. PMID: 21466597
Recently, a massive loss of both hypocretin and melanin-concentrating hormone (MCH) neurones was found in the hypothalamus of Parkinson's disease (PD) patients. Because both hypocretin and MCH play a key...
3.
Rozing M, Houwing-Duistermaat J, Slagboom P, Beekman M, Frolich M, de Craen A, et al.
J Clin Endocrinol Metab . 2010 Aug; 95(11):4979-84. PMID: 20739380
Context: A relation between low thyroid activity and prolonged life span in humans has been observed. Several studies have demonstrated hereditary and genetic influences on thyroid function. Objective: The objective...
4.
Goekoop R, Kloppenburg M, Kroon H, Frolich M, Huizinga T, Westendorp R, et al.
Osteoarthritis Cartilage . 2010 Apr; 18(7):942-7. PMID: 20417290
Objective: We investigated whether innate differences in cytokine response were associated with the absence of osteoarthritis (OA) in old age. Design: In 82 participants from a cross-sectional birth cohort, radiographs...
5.
Snel M, Sleddering M, Pijl H, Nieuwenhuizen W, Frolich M, Havekes L, et al.
Eur J Clin Nutr . 2010 Feb; 64(4):419-23. PMID: 20179727
Background: Sphingolipids, like phytosphingosine (PS) are part of cellular membranes of yeasts, vegetables and fruits. Addition of PS to the diet decreases serum cholesterol and free fatty acid (FFA) levels...
6.
Henneman P, Janssens A, Zillikens M, Frolich M, Frants R, Oostra B, et al.
J Intern Med . 2009 Nov; 267(4):402-9. PMID: 19912464
Objective: Plasma adiponectin is negatively correlated with metabolic syndrome (MetS) components obesity and insulin sensitivity. Here, we set out to evaluate the effect of menopause on the association of plasma...
7.
Aziz N, Pijl H, Frolich M, Schroder-van der Elst J, van der Bent C, Roelfsema F, et al.
Eur J Neurol . 2009 Oct; 17(2):280-8. PMID: 19845749
Background And Purpose: Huntington's disease (HD) is a fatal hereditary neurodegenerative disorder caused by an increased CAG repeat size in the huntingtin gene. Apart from neurological impairment, the disease is...
8.
van Vliet P, Westendorp R, Eikelenboom P, Comijs H, Frolich M, Bakker E, et al.
Neurology . 2009 Sep; 73(9):681-7. PMID: 19720974
Background: Variation in APOE genotype is a determinant of Alzheimer disease (AD), but the risk associated with variation in plasma apoE levels has yet to be determined. Here, we studied...
9.
May L, van Bodegom D, Kuningas M, Meij J, de Craen A, Frolich M, et al.
Cytokine . 2009 Feb; 45(3):184-9. PMID: 19185506
Innate propensity of immune activation is reflected in production of pro- and anti-inflammatory cytokines upon stimulation of Toll-like receptors (TLR) in whole-blood stimulation assays. The validity of the whole-blood stimulation...
10.
Finken M, Keijzer-Veen M, Dekker F, Frolich M, Walther F, Romijn J, et al.
Arch Dis Child Fetal Neonatal Ed . 2008 May; 93(6):F442-7. PMID: 18450806
Background: A single course of maternal glucocorticoid treatment is effective in reducing neonatal mortality after preterm birth. However, in animals, maternal glucocorticoid treatment is associated with lifelong hyperglycaemia and hypertension,...