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H H Lemkes

Explore the profile of H H Lemkes including associated specialties, affiliations and a list of published articles. Areas
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Articles 72
Citations 652
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Recent Articles
1.
Maassen J, t Hart L, Janssen G, Reiling E, Romijn J, Lemkes H
Biochem Soc Trans . 2006 Oct; 34(Pt 5):819-23. PMID: 17052206
Multiple pathogenic pathways are able to deregulate glucose homoeostasis leading to diabetes. The 3243A>G mutation in the mtDNA (mitochondrial DNA)-encoded tRNALeu,UUR gene was found by us to be associated with...
2.
Maassen J, Lemkes H, Losekoot M
Ned Tijdschr Geneeskd . 2001 Aug; 145(28):1352-3. PMID: 11484433
Maturity-onset diabetes of the young (MODY) exhibits an autosomal dominant pattern of inheritance and can be divided in at least five subtypes (MODY 1 to 5), each subtype being caused...
3.
Diamant M, Hanemaaijer R, Verheijen J, Smit J, Radder J, Lemkes H
Diabet Med . 2001 Jul; 18(5):423-4. PMID: 11472458
No abstract available.
4.
Maassen J, van den Ouweland J, Losekoot M, Lemkes H
Ned Tijdschr Geneeskd . 2001 Jul; 145(24):1153-4. PMID: 11433662
MIDD is a maternally inherited disorder with diabetes and impaired hearing due to a reduced perception of high tones. The disorder is caused by an A to G mutation at...
5.
Maassen J, van Essen E, van den Ouweland J, Lemkes H
Exp Clin Endocrinol Diabetes . 2001 Jun; 109(3):127-34. PMID: 11409293
This review provides a compact overview on the contribution of mutations in mtDNA to the pathogenesis of diabetes mellitus, with emphasis on the A3243G mutation in the tRNA(Leu, UUR) gene....
6.
van Essen E, Roep B, t Hart L, Jansen J, van den Ouweland J, Lemkes H, et al.
Diabet Med . 2001 Feb; 17(12):841-7. PMID: 11168326
Aim: Maternally inherited diabetes and deafness (MIDD) associates with a mutation at position 3243 in mitochondrial DNA. Phenotypic expression of MIDD includes Type 1-like and Type 2-like diabetes. This study...
7.
Smets Y, van der Pijl J, Frolich M, Ringers J, de Fijter J, Lemkes H
Transplantation . 2000 May; 69(7):1322-7. PMID: 10798747
Background: Monitoring of insulin secretion and sensitivity after pancreas transplantation remains a practical problem. Methods: We introduced the simple structural model, continuous infusion of glucose with model assessment (CIGMA), to...
8.
Smets Y, Westendorp R, van der Pijl J, de Charro F, Ringers J, de Fijter J, et al.
Lancet . 1999 Jun; 353(9168):1915-9. PMID: 10371569
Background: Long-term prognosis of patients with type-1 diabetes mellitus and end-stage renal failure appears to be better after kidney transplantation compared with dialysis. Controversy exists about the additional benefit of...
9.
van der Pijl J, Lemkes H, Frolich M, van der Woude F, van der Meer F, van Es L
J Am Soc Nephrol . 1999 Jun; 10(6):1331-6. PMID: 10361873
In diabetic nephropathy, heparan sulfate glycosaminoglycan side chains are reduced in glomerular basement membranes proportionally to the degree of proteinuria. Recently, it was demonstrated that additional therapy with danaparoid sodium,...
10.
Vleming L, van der Pijl J, Lemkes H, Westendorp R, Maassen J, Daha M, et al.
Clin Nephrol . 1999 Apr; 51(3):133-40. PMID: 10099885
Background: The insertion-deletion (I/D) polymorphism of the angiotensin converting enzyme gene is a diallelic polymorphism that constitutes a genetic influence on the progression of renal diseases such as IgA nephropathy....