M E Reff
Overview
Explore the profile of M E Reff including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
17
Citations
614
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0
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Recent Articles
1.
Reff M, Heard C
Crit Rev Oncol Hematol
. 2001 Oct;
40(1):25-35.
PMID: 11578914
Although monoclonal antibodies have high specificity, their usefulness in the clinic, especially against solid tumors, has been limited. This arises in part from the inability of antibody molecules to penetrate...
2.
Nakamura T, Kloetzer W, Brams P, Hariharan K, Chamat S, Cao X, et al.
Int J Immunopharmacol
. 2000 Feb;
22(2):131-41.
PMID: 10684997
CD23, the low affinity receptor for IgE (FcvarepsilonRII), is involved in regulation of IgE synthesis by B-lymphocytes. Five monoclonal antibodies to human CD23 were generated from cynomolgus macaques immunized with...
3.
Yron I, Deckert M, Reff M, Munshi A, Schwartz M, Altman A
Cell Adhes Commun
. 1999 May;
7(1):1-11.
PMID: 10228731
The proto-oncogene product p95Vav (Vav) undergoes rapid phosphorylation on tyrosine following stimulation of the T or B cell antigen receptor, and in response to a variety of other cell surface...
4.
Preston M, Gerceker A, Reff M, Pier G
Infect Immun
. 1998 Aug;
66(9):4137-42.
PMID: 9712759
The heavy- and light-chain variable regions from a murine monoclonal antibody that recognize Pseudomonas aeruginosa serogroup O6 lipopolysaccharide (LPS) were used to generate a series of chimeric mouse-human monoclonal antibodies...
5.
Reff M, Carner K, Chambers K, Chinn P, Leonard J, Raab R, et al.
Blood
. 1994 Jan;
83(2):435-45.
PMID: 7506951
Murine monoclonal antibody 2B8 specifically recognizes the CD20 phosphoprotein expressed on the surface of normal B lymphocytes and B-cell lymphomas. The light- and heavy-chain variable regions of 2B8 were cloned,...
6.
Reff M
Curr Opin Biotechnol
. 1993 Oct;
4(5):573-6.
PMID: 7764208
Successful high-level expression of recombinant immunoglobulins has now been reported in several different types of mammalian cells. This has been achieved using random integration of immunoglobulin genes co-linked with a...
7.
Gennaro D, Hoffstein S, Marks G, Ramos L, Oka M, Reff M, et al.
Proc Soc Exp Biol Med
. 1991 Oct;
198(1):591-8.
PMID: 1909792
Tissue-type plasminogen activator (tPA) is a serine protease which cleaves plasminogen to its active form, plasmin. tPA plays a physiologic role in hemostasis, wound healing, and embryogenesis. Therapeutically, recombinant human...
8.
Gimmi E, Reff M, Deckman I
Nucleic Acids Res
. 1989 Sep;
17(17):6983-98.
PMID: 2571127
RNase mapping experiments show that the bovine growth hormone (bGH) poly(A) region forms an extensive hairpin loop. Mutants were prepared to change poly(A) region pre-mRNA structure and cleavage site efficiency...
9.
Pierard L, Garcia Quintana L, Reff M, Bollen A
DNA
. 1989 Jun;
8(5):321-8.
PMID: 2504571
To investigate the structure-function relationship in tissue-type plasminogen activator (t-PA) and urokinase-type plasminogen activator (u-PA), four hybrid sequences were amplified and overexpressed in a mouse myeloma cell line. The following...
10.
Lijnen H, Pierard L, Reff M, Gheysen D
Thromb Res
. 1988 Dec;
52(5):431-41.
PMID: 3146822
A chimaeric recombinant plasminogen activator (rscu-PA- K2) obtained by insertion of the second kringle (K2) of tissue-type plasminogen activator (t-PA) (amino acids 173-262) between residues Asp130 and Ser139 of single...