M C Tobes
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Explore the profile of M C Tobes including associated specialties, affiliations and a list of published articles.
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23
Citations
440
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Recent Articles
1.
Di Carli M, Tobes M, Mangner T, Levine A, Muzik O, Chakroborty P, et al.
N Engl J Med
. 1997 Apr;
336(17):1208-15.
PMID: 9110908
Background: The role of cardiac sympathetic nerves in regulating coronary blood flow is controversial. We sought to determine the degree to which cardiac efferent sympathetic signals modulate coronary blood flow....
2.
Levine T, Levine A, Goldberg A, Tobes M, Narins B, Goldstein S, et al.
Am J Cardiol
. 1997 Jan;
79(1):105-6.
PMID: 9024753
For transplant wait-list patients with end-stage congestive heart failure, reversibility of pulmonary hypertension tested with acute administration of vasodilators is a prerequisite to listing for transplantation. We have shown that...
3.
Tobes M, Fig L, Carey J, Geatti O, Sisson J, Shapiro B
J Nucl Med
. 1989 Sep;
30(9):1476-82.
PMID: 2769403
Iodine-131 metaiodobenzylguanidine (MIBG) is an effective agent for the scintigraphic portrayal of pheochromocytomas of all types. Iodine-131 MIBG is a relatively stable radiopharmaceutical that is primarily excreted in the urine....
4.
Sisson J, Wieland D, Sherman P, Mangner T, Tobes M, Jacques Jr S
J Nucl Med
. 1987 Oct;
28(10):1620-4.
PMID: 3655914
The radiopharmaceutical, metaiodobenzylguanidine (MIBG) acts as an analog of norepinephrine (NE). Experiments in rats were carried out to determine how closely the movements of [125I]MIBG in the heart mimicked those...
5.
Jaques Jr S, Tobes M, Sisson J
Cancer Res
. 1987 Aug;
47(15):3920-8.
PMID: 3607739
Radioiodinated m-iodobenzylguanidine (MIBG), a scintigraphic agent used in the detection of human pheochromocytomas, is thought to utilize the same uptake and retention mechanism(s) as norepinephrine (NE). Using primary cultures from...
6.
7.
Jaques Jr S, Tobes M
J Cell Physiol
. 1986 Aug;
128(2):261-70.
PMID: 3733889
Primary cell cultures from 18 human pheochromocytomas were maintained in culture for 10 to 12 days and characterized. The cell yields ranged from 1.0 to 60.1 X 10(6) cells/g wet...
8.
Shulkin B, Shapiro B, Tobes M, Shen S, Wieland D, Meyers L, et al.
J Nucl Med
. 1986 Jul;
27(7):1138-42.
PMID: 3723189
Iodine-123-4-amino-3-iodobenzylguanidine ([123I]AIBG), an analog of 123I metaiodobenzylguanidine ([123I]MIBG), has an advantage in having a more rapid and simple synthesis. This, combined with animal data that suggested a greater affinity of...
9.
Mangner T, Tobes M, Wieland D, Sisson J, Shapiro B
J Nucl Med
. 1986 Jan;
27(1):37-44.
PMID: 3941363
Iodine-131 metaiodobenzylguanidine ([131I]MIBG) is used to image and treat human pheochromocytoma. As part of a pharmacodynamic study of this agent, we have evaluated its excretion and metabolism in nine pheochromocytoma...
10.
Gildersleeve D, Tobes M, Natale R
Clin Chem
. 1985 Dec;
31(12):1979-84.
PMID: 4064286
We describe a "high-performance" reversed-phase ion-pair liquid-chromatographic procedure for measuring methylglyoxal bis(guanylhydrazone) (MGBG) in plasma, urine, and bone-marrow leukocytes. Specimens of plasma and bone-marrow leukocytes are deproteinized with perchloric acid,...